pyrazinoic acid

Known as: pyrazine-2-carboxylic acid, pyrazinecarboxylic acid 
 
National Institutes of Health

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2012
2012
Pyrazinamide is one of the most important drugs in the treatment of latent Mycobacterium tuberculosis infection. The emergence of… (More)
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2011
Highly Cited
2011
Pyrazinamide (PZA) is a first-line tuberculosis drug that plays a unique role in shortening the duration of tuberculosis… (More)
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2011
2011
Pyrazinoic acid, the active form of the first-line antituberculosis drug pyrazinamide, decreased the proton motive force and… (More)
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2009
2009
Pyrazinamide (PZA) is active against M. tuberculosis and is a first line agent for the treatment of human tuberculosis. PZA is… (More)
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2007
2007
The activity of different analogs of pyrazinamide on Mycobacterium tuberculosis fatty acid synthase type I (FASI) in replicating… (More)
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2003
Highly Cited
2003
Pyrazinamide is an important sterilizing drug that shortens tuberculosis (TB) therapy. However, the mechanism of action of… (More)
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2002
Highly Cited
2002
The effects of low extracellular pH and intracellular accumulation of weak organic acids were compared with respect to fatty acid… (More)
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2000
Highly Cited
2000
Tuberculosis treatment is shortened to six months by the indispensable addition of pyrazinamide (PZA) to the drug regimen that… (More)
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1999
Highly Cited
1999
Pyrazinamide (PZA) is an important antituberculosis drug. Unlike most antibacterial agents, PZA, despite its remarkable in vivo… (More)
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1997
Highly Cited
1997
Pyrazinamide (PZA) is a first-line drug for short-course tuberculosis therapy. Resistance to PZA is usually accompanied by loss… (More)
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