pyrazinoate
National Institutes of Health
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This issue provides a clinical overview of gout focusing on prevention, diagnosis, treatment, practice improvement, and patient…
Inhibition of [14C]-urate uptake by uricosuric and antiuricosuric agents was investigated in human brush-border membrane vesicles…
[14C]urate and p-[14C]aminohippurate (PAH) uptake by human brush-border membrane vesicles (BBMV) were measured in the presence of…
The transport of urate and p-aminohippurate (PAH) across the pig renal brush border membrane was investigated using membrane…
Pyrazinoate (PZA) is an organic anion actively reabsorbed and secreted in the mammalian kidney. In experiments with rabbit renal…
Cisplatin, an effective antineoplastic agent, is toxic to the kidney. Since the kidney's vulnerability to cisplatin may originate…
The inhibitory effects of p-aminohippurate and pyrazinoate (PZA) on the transport of salicylate were studied by free-flow…
The transport of urate and p-aminohippurate (PAH) was evaluated in brush border membrane vesicles from the rat renal cortex. The…
We investigated the acute effect of an orally administered uricosuric natriuretic agent (SKF-62698) on renal urate transport in…
These experiments were designed to define the renal disposition of pyrazinoic acid in a nonhuman primate that is phylogenetically…