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Significance of Increased Phosphatase Activity of Bone at the Site of Osteoplastic Metastases Secondary to Carcinoma of the Prostate Gland
Recent determinations of serum phosphatase activity in patients with cancer (1, 2, 3) suggest that values obtained in cases with widespread osteoplastic metastases are, in general, significantly… Expand
Uric acid nephrolithiasis.
Abstract Available estimates indicate that about 10 per cent of all renal calculi encountered in the U.S.A. as a whole are composed of uric acid and that the prevalence of uric acid nephrolithiasis… Expand
Renal mechanisms for regulation of uric acid excretion, with special reference to normal and gouty man.
T HIS REVIEW BEGINS with a brief description of the historical development of the long sequence of hypotheses relating to the disposition of uric acid by the kidneys. Of course these evolved in… Expand
Serum alkaline phosphatase activity in diseases of the skeletal and hepatobiliary systems. A consideration of the current status.
- A. Gutman
- Medicine
- The American journal of medicine
- 1 December 1959
T HE blood plasma of normal man contains representatives of two classes of “nonspecific” phosphomonoesterases, one exhibiting optimum activity at pH ca. 9 with substrate in high concentration [I+?],… Expand
FRACTIONATION OF SERUM PROTEINS IN HYPERPROTEINEMIA, WITH SPECIAL REFERENCE TO MULTIPLE MYELOMA.
- A. Gutman, D. Moore, E. Gutman, V. McClellan, E. Kabat
- Medicine
- The Journal of clinical investigation
- 1 November 1941
Investigation of the serum proteins in disease is handicapped by lack of clinically applicable methods for resolving the complex system of proteins present in blood serum into homogeneous components.… Expand
AN ABNORMALITY OF GLUTAMINE METABOLISM IN PRIMARY GOUT.
Abstract Six gouty and four nongouty men were given a standard oral dose of glycine-N 15 , and the incorporation of isotope into the urinary uric acid, urea, ammonia and creatinine was determined, in… Expand
EFFECT OF DISEASE OF THE LIVER AND BILIARY TRACT UPON THE PHOSPHATASE ACTIVITY OF THE SERUM.
- A. Gutman, K. Olson, E. Gutman, C. A. Flood
- Medicine
- The Journal of clinical investigation
- 1940
The present study deals with the influence of common affections of the liver and biliary tract upon the level of serum phosphatase activity in the adult. It is an analysis of our observations during… Expand
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