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phosphoramidon

Known as: N-(alpha-L-rhamnopyranosyloxyhydroxyphosphinyl)-L- leucyl-L-tryptophan 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Anti-Bacterial AgentsGlycopeptidesProtease Inhibitors

Papers overview

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2004
2004
Interleukin‐1β attenuates endothelin B receptor‐mediated airway contractions in a murine in vitro model of asthma: roles of endothelin converting enzyme and mitogen‐activated protein kinase pathways
Background Asthma is a chronic airway disease, known to involve several inflammatory mediators. Little is known about how these… 
2000
2000
Cytokines enhance airway smooth muscle contractility in response to acetylcholine and neurokinin A
In vivo airway hyperresponsiveness has been demonstrated following inhalation of specific cytokines in normal individuals… 
1998
1998
Effects of SR 140333 and SR 48968 on antigen and substance P‐induced activation of guinea‐pig alveolar macrophages
Tachykinins, such as substance P, might be involved in the development of airway hyperresponsiveness and airway inflammation. 
Highly Cited
1997
Highly Cited
1997
Intravascular and interstitial degradation of bradykinin in isolated perfused rat heart
1 Bradykinin (BK) has been shown to exert cardioprotective effects which are potentiated by inhibitors of angiotensin I… 
1995
1995
Differential effects of phosphoramidon on contractile responses to angiotensin II in rat blood vessels
1 Cumulative concentration‐tension response (C‐R) curves to angiotensin II (AII), big endothelin‐1 (big ET‐1), ET‐1 and arginine… 
1995
1995
Effect of an inhaled neutral endopeptidase inhibitor, phosphoramidon, on baseline airway calibre and bronchial responsiveness to bradykinin in asthma.
BACKGROUND--Bradykinin is a potent vasoactive peptide which has been proposed as an important inflammatory mediator in asthma… 
1992
1992
Human brain contains a metalloprotease that converts big endothelin‐1 to endothelin‐1 and is inhibited by phosphoramidon and EDTA
Incubation of big endothelin‐1 (bET‐1) with protein derived from the detergent‐extracted 100,000 g pellet prepared from human… 
1991
1991
Human big endothelin releases prostacyclin in vivo and in vitro through a phosphoramidon-sensitive conversion to endothelin-1.
Human big endothelin (big ET) and endothelin-1 (ET-1) induce similar increases in left ventricular systolic pressure in the… 
1991
1991
DISTRIBUTION AND INHIBITION OF NEUTRAL METALLOENDOPEPTIDASE (NEP) (EC 3.4.24.11), THE MAJOR DEGRADATIVE ENZYME FOR ATRIAL NATRIURETIC PEPTIDE, IN THE RAT KIDNEY
1. Atrial natriuretic peptide (ANP) is degraded by neutral metalloendopeptidase (NEP) (EC 3.4.24.11) and the kidney is a major… 
Highly Cited
1989
Highly Cited
1989
Tachykinins mediate bronchoconstriction elicited by isocapnic hyperpnea in guinea pigs.
We tested the hypothesis that tachykinins mediate hyperpnea-induced bronchoconstriction (HIB) in 28 guinea pigs. Stimulus… 
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