phospholipase A2-alpha

Known as: cPLA2-Alpha, Phospholipases, cPLA2, PLA2G4A 
Cytosolic phospholipase A2 (749 aa, ~85 kDa) is encoded by the human PLA2G4A gene. This protein is involved in arachidonic acid metabolism.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1949-2018
0204019492017

Papers overview

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Highly Cited
2014
Highly Cited
2014
Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults, with an uncertain clinical outcome. The… (More)
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2010
2010
BACKGROUND Phospholipase A2 (PLA2) and cyclooxygenase 2 (COX2) are the two key enzymes in the metabolism of polyunsaturated fatty… (More)
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2008
2008
PURPOSE Cytosolic phospholipase A2-alpha (cPLA2-alpha) provides intracellular arachidonic acid to supply both cyclooxygenase and… (More)
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2007
2007
The regulated generation of prostaglandins from endothelial cells is critical to vascular function. Here we identify a novel… (More)
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Highly Cited
1997
Highly Cited
1997
Phospholipase A2 (PLA2) enzymes are critical regulators of prostaglandin and leukotriene synthesis and can directly modify the… (More)
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Highly Cited
1997
Highly Cited
1997
Phospholipase A2 (PLA2) comprises a superfamily of enzymes that hydrolyse the ester bond of phospholipids at the sn-2 position… (More)
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Highly Cited
1996
Highly Cited
1996
Phospholipase A2 (PLA2) is the key enzyme that initiates the arachidonic acid cascade, which leads to the generation of multiple… (More)
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Highly Cited
1992
Highly Cited
1992
Storage triacylglycerols (TAG) in plant seeds are present in small discrete intracellular organelles called oil bodies. An oil… (More)
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Highly Cited
1980
Highly Cited
1980
When rabbit peritoneal neutrophils were treated with glucocorticoids, their chemotactic response to stimulation by the… (More)
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1977
1977
The complete amino acid sequence of Crotalus adamanteus venom phospholipase A2-alpha has been determined by analysis of the five… (More)
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