Cytosolic Phospholipase A2
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Docosahexaenoic acid (DHA) is one of the major ingredients of fish oil and has been reported to have anti‐inflammatory properties… Expand Macrophage migration inhibitory factor (MIF) is an important pro-inflammatory mediator with the unique ability to counter… Expand When cells are exposed to certain external stimuli, arachidonic acid (AA) is released from the membrane and serves as a precursor… Expand Lipid bodies are inducible lipid domains abundantly present in leukocytes engaged in inflammation. They are rich in esterified… Expand The Ca2+-sensitive 85-kDa cytosolic phospholipase A2 (cPLA2) is responsible for thrombin-stimulated mobilization of arachidonic… Expand Intracellular signalling events that govern endothelial responses to shear are incompletely defined. In this study confluent… Expand BACKGROUND AND PURPOSE
Phospholipid breakdown has been reported to be an early event in the brain after global cerebral ischemia… Expand Cytosolic phospholipase A2 (cPLA2) is activated by a wide variety of stimuli to release arachidonic acid, the precursor of the… Expand Treatment of cells with agents that stimulate the release of arachidonic acid causes increased serine phosphorylation and… Expand The major dithiothreitol-resistant phospholipase A2 activity present in the cytosol of U937 cells has been purified greater than… Expand