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Cytosolic Phospholipase A2

Known as: PLA(2)-IV, Phospholipase A2G4, Phospholipase A2IV 
A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Docosahexaenoic acid (DHA) is one of the major ingredients of fish oil and has been reported to have anti‐inflammatory properties… Expand
Highly Cited
1999
Highly Cited
1999
Macrophage migration inhibitory factor (MIF) is an important pro-inflammatory mediator with the unique ability to counter… Expand
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Highly Cited
1999
Highly Cited
1999
  • T. Hirabayashi, K. Kume, +4 authors Takao Shimizu
  • The Journal of Biological Chemistry
  • 1999
  • Corpus ID: 38448745
When cells are exposed to certain external stimuli, arachidonic acid (AA) is released from the membrane and serves as a precursor… Expand
Highly Cited
1998
Highly Cited
1998
Lipid bodies are inducible lipid domains abundantly present in leukocytes engaged in inflammation. They are rich in esterified… Expand
Highly Cited
1996
Highly Cited
1996
The Ca2+-sensitive 85-kDa cytosolic phospholipase A2 (cPLA2) is responsible for thrombin-stimulated mobilization of arachidonic… Expand
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Highly Cited
1996
Highly Cited
1996
Intracellular signalling events that govern endothelial responses to shear are incompletely defined. In this study confluent… Expand
Highly Cited
1996
Highly Cited
1996
BACKGROUND AND PURPOSE Phospholipid breakdown has been reported to be an early event in the brain after global cerebral ischemia… Expand
Highly Cited
1995
Highly Cited
1995
  • A. Schievella, M. Regier, William L. Smith, Lih-Ling Lin
  • The Journal of Biological Chemistry
  • 1995
  • Corpus ID: 25202329
Cytosolic phospholipase A2 (cPLA2) is activated by a wide variety of stimuli to release arachidonic acid, the precursor of the… Expand
Highly Cited
1993
Highly Cited
1993
Treatment of cells with agents that stimulate the release of arachidonic acid causes increased serine phosphorylation and… Expand
Highly Cited
1990
Highly Cited
1990
The major dithiothreitol-resistant phospholipase A2 activity present in the cytosol of U937 cells has been purified greater than… Expand