Cytosolic Phospholipase A2

Known as: PLA(2)-IV, Phospholipase A2G4, Phospholipase A2IV 
A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
010203019902018

Papers overview

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Highly Cited
2000
Highly Cited
2000
The 85-kDa cytosolic phospholipase A(2) (cPLA(2)) mediates agonist-induced arachidonic acid release and eicosanoid production… (More)
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Highly Cited
1999
Highly Cited
1999
Macrophage migration inhibitory factor (MIF) is an important pro-inflammatory mediator with the unique ability to counter… (More)
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Highly Cited
1999
Highly Cited
1999
When cells are exposed to certain external stimuli, arachidonic acid (AA) is released from the membrane and serves as a precursor… (More)
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Highly Cited
1998
Highly Cited
1998
Lipid bodies are inducible lipid domains abundantly present in leukocytes engaged in inflammation. They are rich in esterified… (More)
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Highly Cited
1997
Highly Cited
1997
Mutations in Ras family members that confer oncogenic potential are frequently observed in specific human cancers. We report that… (More)
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Highly Cited
1996
Highly Cited
1996
Phospholipase A2 (PLA2) is the key enzyme that initiates the arachidonic acid cascade, which leads to the generation of multiple… (More)
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Highly Cited
1996
Highly Cited
1996
The Ca2+-sensitive 85-kDa cytosolic phospholipase A2 (cPLA2) is responsible for thrombin-stimulated mobilization of arachidonic… (More)
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Highly Cited
1995
Highly Cited
1995
Cytosolic phospholipase A2 (cPLA2) is activated by a wide variety of stimuli to release arachidonic acid, the precursor of the… (More)
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Highly Cited
1993
Highly Cited
1993
Treatment of cells with agents that stimulate the release of arachidonic acid causes increased serine phosphorylation and… (More)
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Highly Cited
1990
Highly Cited
1990
The major dithiothreitol-resistant phospholipase A2 activity present in the cytosol of U937 cells has been purified greater than… (More)
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