Arachidonic Acid Metabolism Pathway
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Mammalian genomes encode genes for more than 30 phospholipase A₂s (PLA₂s) or related enzymes, which are subdivided into several… Expand Apigenin 7-O-beta-D-glucopyranuronide (1), luteolin 7-O-beta-D-glucopyranuronide (2), m-hydroxybenzyl beta-D-glucoside (3), and… Expand SummaryPrevious studies have demonstrated that inhibitors of the arachidonic acid metabolism block migration and sensitise human… Expand Sphingolipid metabolites such as sphingosine regulate cell functions including cell death and arachidonic acid (AA) metabolism. D… Expand Summary Previous studies have demonstrated that inhibitors of the arachidonic acid metabolism block migration and sensitise human… Expand Dual 5-LOX/COX inhibitors are potential new drugs to treat inflammation. They act by blocking the formation of both… Expand The changes of the levels of LTC4, PGI2 and TXA2 in the liver tissue in SD rats with GaIN/LPS-induced acute liver injury was… Expand Glucocorticosteroids are used as anti-inflammatory agents in a range of diseases, however, their mechanism of action is unknown… Expand Bovine neutrophils were preincubated with recombinant bovine interferon‐γ (rbolFN‐γ), and the molecular events leading to… Expand Kinins, antidiuretic hormone, and several of their analogues stimulated contractile rat kidney mesangial cells growing in culture… Expand