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Phospholipases A2

Known as: Phospholipases A2 [Chemical/Ingredient], phosphatidolipase, PLA2 
Various types of calcium-dependent or -independent Phospholipases A2 hydrolyze phospholipids. Group I, II, and III phospholipases are secreted, while… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (18)

7-hydroxycoumarinyl ester hydrolaseBnSP-6Lys49-phospholipase A2, Bothrops lternatusMVL-PLA2, Macrovipera lebetina

Broader (3)

Carboxylic Ester HydrolasesPhospholipases Acarboxylesterase
Cytosolic Phospholipase A2HydrolysisIn BloodPLA2G10 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Atherogenic properties of LDL particles modified by human group X secreted phospholipase A2 on human endothelial cell function
Increasing evidence suggests that se‐creted phospholipases A2 (sPLA2s) play an important role in the pathophysiology of… 
Highly Cited
1992
Highly Cited
1992
Heterologous gene expression in Aspergillus niger: a glucoamylase-porcine pancreatic prophospholipase A2 fusion protein is secreted and processed to yield mature enzyme.
Highly Cited
1991
Highly Cited
1991
Interfacial catalysis by phospholipase A2: dissociation constants for calcium, substrate, products, and competitive inhibitors.
Interpretation of the kinetics of interfacial catalysis in the scooting mode as developed in the first paper of this series [Berg… 
Highly Cited
1989
Highly Cited
1989
Possible involvement of cytoskeleton in collagen-stimulated activation of phospholipases in human platelets.
Highly Cited
1985
Highly Cited
1985
Inhibition of human platelet phospholipase A2 activity by unsaturated fatty acids.
Phospholipase A2 (PLA2; phosphatide 2-acylhydrolase, EC 3.1.1.4) activity from human platelets increases significantly when the… 
Highly Cited
1983
Highly Cited
1983
How a nerve fiber repairs its cut end: involvement of phospholipase A2.
Following transection of a giant axon, the nerve membrane at the cut end is resealed within 5 to 30 minutes. This membrane… 
Highly Cited
1983
Highly Cited
1983
Inhibition of phospholipase A2 and platelet aggregation by glycyrrhizin, an antiinflammation drug.
We studied the effect of glycyrrhizin, a compound known as an anti-inflammatory and antiallergic drug, on the membrane… 
Highly Cited
1980
Highly Cited
1980
Inhibition of highly purified mammalian phospholipases A2 by non-steroidal anti-inflammatory agents. Modulation by calcium ions.
Highly purified Ca2+-dependent phospholipases A2 that were isolated from human platelets, rabbit alveolar macrophages and… 
Highly Cited
1977
Highly Cited
1977
Thrombin, collagen and A23187 stimulated endogenous platelet arachidonate metabolism: differential inhibition by PGE1, local anesthetics and a serine-protease inhibitor.
Highly Cited
1975
Highly Cited
1975
The interaction of phospholipase A2 with micellar interfaces. The role of the N-terminal region.
The localization of the previously postulated interface recognition site (IRS) in porcine pancreatic phospholipase A2, required… 
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