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Phospholipases A2

Known as: Phospholipases A2 [Chemical/Ingredient], phosphatidolipase, PLA2 
Various types of calcium-dependent or -independent Phospholipases A2 hydrolyze phospholipids. Group I, II, and III phospholipases are secreted, while… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (18)

7-hydroxycoumarinyl ester hydrolaseBnSP-6Lys49-phospholipase A2, Bothrops lternatusMVL-PLA2, Macrovipera lebetina

Broader (3)

Carboxylic Ester HydrolasesPhospholipases Acarboxylesterase
Cytosolic Phospholipase A2HydrolysisIn BloodPLA2G10 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Atherogenic properties of LDL particles modified by human group X secreted phospholipase A2 on human endothelial cell function
Increasing evidence suggests that se‐creted phospholipases A2 (sPLA2s) play an important role in the pathophysiology of… 
Highly Cited
2002
Highly Cited
2002
Secretory phospholipases A2 induce cytokine release from blood and synovial fluid monocytes
Secretory phospholipases A2 (sPLA2) are released in the blood of patients with various inflammatory diseases and exert… 
Highly Cited
1998
Highly Cited
1998
Hydrolysis of surfactant-associated phosphatidylcholine by mammalian secretory phospholipases A2.
Hydrolysis of surfactant-associated phospholipids by secretory phospholipases A2 is an important potential mechanism for… 
Highly Cited
1997
Highly Cited
1997
High specificity of human secretory class II phospholipase A2 for phosphatidic acid.
Lysophosphatidic acid (LPA) is a potent lipid second messenger which stimulates platelet aggregation, cell proliferation and… 
Highly Cited
1996
Highly Cited
1996
Purification of a Novel Calcium-independent Phospholipase A2 from Rabbit Kidney*
We have recently identified a cytosolic calcium-independent phospholipase A2 (PLA2) that represents the major measurable PLA2… 
Highly Cited
1993
Highly Cited
1993
Structural determinants of haloenol lactone-mediated suicide inhibition of canine myocardial calcium-independent phospholipase A2.
Haloenol lactones are potent mechanism-based inhibitors of a novel class of calcium-independent phospholipases A2 which have been… 
Highly Cited
1992
Highly Cited
1992
Detection of three distinct phospholipases A2 in cultured mast cells.
Phospholipase A2 activity in lysates of mast cells such as rat mastocytoma RBL-2H3 cells and mouse bone marrow-derived IL-3… 
Highly Cited
1989
Highly Cited
1989
Possible involvement of cytoskeleton in collagen-stimulated activation of phospholipases in human platelets.
Highly Cited
1987
Highly Cited
1987
Selective release of phospholipase A2 and lysophosphatidylserine-specific lysophospholipase from rat platelets.
Rat platelets released phospholipase A2 and lysophospholipase upon activation with thrombin or ADP. The release of phospholipases… 
Highly Cited
1975
Highly Cited
1975
The interaction of phospholipase A2 with micellar interfaces. The role of the N-terminal region.
The localization of the previously postulated interface recognition site (IRS) in porcine pancreatic phospholipase A2, required… 
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