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Phospholipases A2

Known as: Phospholipases A2 [Chemical/Ingredient], phosphatidolipase, PLA2 
Various types of calcium-dependent or -independent Phospholipases A2 hydrolyze phospholipids. Group I, II, and III phospholipases are secreted, while… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (18)

7-hydroxycoumarinyl ester hydrolaseBnSP-6Lys49-phospholipase A2, Bothrops lternatusMVL-PLA2, Macrovipera lebetina

Broader (3)

Carboxylic Ester HydrolasesPhospholipases Acarboxylesterase
Cytosolic Phospholipase A2HydrolysisIn BloodPLA2G10 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Secreted phospholipase A2 revisited.
Phospholipase A(2) (PLA(2)) catalyses the hydrolysis of the sn-2 position of glycerophospholipids to yield fatty acids and… 
Highly Cited
2002
Highly Cited
2002
Interfacial Kinetic and Binding Properties of the Complete Set of Human and Mouse Groups I, II, V, X, and XII Secreted Phospholipases A2 *
Expression of the full set of human and mouse groups I, II, V, X, and XII secreted phospholipases A2 (sPLA2s) in Escherichia coli… 
Review
1999
Review
1999
Receptors for a growing family of secreted phospholipases A2.
Highly Cited
1998
Highly Cited
1998
A Novel Calcium-independent Phospholipase A2, cPLA2-γ, That Is Prenylated and Contains Homology to cPLA2 *
We report the cloning and characterization of a novel membrane-bound, calcium-independent PLA2, named cPLA2-γ. The sequence… 
Review
1994
Review
1994
Phosphatidylcholine breakdown and signal transduction.
Review
1993
Review
1993
New insights on mammalian phospholipase A2(s); comparison of arachidonoyl‐selective and ‐nonselective enzymes
With the recent discoveries of novel forms of phospholipases A2 (PLA2S),2 new schemes for the roles of various PLA2S in lipid… 
Review
1993
Review
1993
Extracellular phospholipase A2 expression and inflammation: the relationship with associated disease states.
Human non-pancreatic PLA2 has been the object of intense scrutiny for a relatively short period of time. Its role in physiology… 
Highly Cited
1990
Highly Cited
1990
Purification of a 110-kilodalton cytosolic phospholipase A2 from the human monocytic cell line U937.
The major dithiothreitol-resistant phospholipase A2 activity present in the cytosol of U937 cells has been purified greater than… 
Review
1989
Review
1989
A model to explain the pharmacological effects of snake venom phospholipases A2.
Highly Cited
1986
Highly Cited
1986
Phospholipase A2 and phospholipase C are activated by distinct GTP-binding proteins in response to alpha 1-adrenergic stimulation in FRTL5 thyroid cells.
In FRTL5 rat thyroid cells, norepinephrine, by interacting with alpha 1-adrenergic receptors, stimulates inositol phosphate… 
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