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carboxylesterase

Known as: Nonspecific Esterase, Carboxylic-Ester Hydrolase, Carboxyesterase 
Carboxylesterase is a serine-dependent esterase with wide substrate specificity. The enzyme is involved in the detoxification of XENOBIOTICS and the… 
National Institutes of Health

Related topics

Related topics

33 relations

Narrower (16)

AcetylcholinesteraseCholinesterasesES-HVEL protein, ratESD protein, human
CES1 protein, humanCES2 protein, humanIn BloodNonspecific esterase stain

Broader (3)

Carboxylic Ester HydrolasesEsterasesSerine Endopeptidases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Anti-Influenza Prodrug Oseltamivir Is Activated by Carboxylesterase Human Carboxylesterase 1, and the Activation Is Inhibited by Antiplatelet Agent Clopidogrel
Oseltamivir is the main medicine recommended by the World Health Organization in anticipation of next influenza pandemic. This… 
Review
1998
Review
1998
The mammalian carboxylesterases: from molecules to functions.
Multiple carboxylesterases (EC 3.1.1.1) play an important role in the hydrolytic biotransformation of a vast number of… 
Highly Cited
1998
Highly Cited
1998
IL‐10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages
Human monocytes cultured with granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) and IL‐13 for 7 days differentiate into… 
Highly Cited
1994
Highly Cited
1994
Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C.
The present studies were undertaken to characterize further the potential role of protein kinase C (PKC) in the regulation of… 
Highly Cited
1993
Highly Cited
1993
Detection of intracellular cytokines by flow cytometry.
Highly Cited
1989
Highly Cited
1989
Cultured human Langerhans cells resemble lymphoid dendritic cells in phenotype and function.
Freshly isolated murine epidermal Langerhans cells (LC) are weak stimulators of resting T cells. Upon culture their phenotype… 
Review
1983
Review
1983
Perturbation of vesicular traffic with the carboxylic ionophore monensin
Highly Cited
1981
Highly Cited
1981
Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts
Highly Cited
1981
Highly Cited
1981
Distinctive functional characteristics of human „T”︁ lymphocytes defined by E rosetting or a monoclonal anti‐T cell antibody
The properties of human lymphocyte fractions isolated either by sheep red cell (E) rosetting or by fluorescence‐activated cell… 
Highly Cited
1979
Highly Cited
1979
Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.
When suspension cultures of human promyelocytic leukemia cells (line HL60) were treated with 12-O-tetradecanoylphorbol 13-acetate… 
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