Skip to search formSkip to main contentSkip to account menu

Carboxylic Ester Hydrolases

Known as: Ester Hydrolases, Carboxylic, Hydrolases, Carboxylic Ester, Carboxylic Ester Hydrolases [Chemical/Ingredient] 
Enzymes which catalyze the hydrolysis of carboxylic acid esters with the formation of an alcohol and a carboxylic acid anion.
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (45)

4-methylumbelliferyl acyl ester hydrolase4-pyridoxolactonase6-Phosphogluconolactonase6-Phosphogluconolactonase Deficiency

Broader (1)

Esterases
In BloodProcess of secretionantagonists & inhibitorschemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
CYP9Q-mediated detoxification of acaricides in the honey bee (Apis mellifera)
Although Apis mellifera, the western honey bee, has long encountered pesticides when foraging in agricultural fields, for two… 
Review
2008
Review
2008
Applications of carboxylesterase activity in environmental monitoring and toxicity identification evaluations (TIEs).
This review has examined a number of issues surrounding the use of carboxylesterase activity in environmental monitoring. It is… 
Review
2006
Review
2006
Structure, function and regulation of carboxylesterases.
Highly Cited
2006
Highly Cited
2006
Antiplatelet Agents Aspirin and Clopidogrel Are Hydrolyzed by Distinct Carboxylesterases, and Clopidogrel Is Transesterificated in the Presence of Ethyl Alcohol
Aspirin (acetylsalicylic acid) and clopidogrel are two major antithrombogenic agents that are widely used for the treatment and… 
Highly Cited
2005
Highly Cited
2005
The Anopheles gambiae detoxification chip: a highly specific microarray to study metabolic-based insecticide resistance in malaria vectors.
Metabolic pathways play an important role in insecticide resistance, but the full spectra of the genes involved in resistance has… 
Review
2005
Review
2005
Mammalian carboxylesterases: from drug targets to protein therapeutics.
Highly Cited
2004
Highly Cited
2004
Methylphenidate Is Stereoselectively Hydrolyzed by Human Carboxylesterase CES1A1
Methylphenidate is an important stimulant prescribed to treat attention-deficit hyperactivity disorder. It has two chiral centers… 
Highly Cited
2003
Highly Cited
2003
Irinotecan pathway genotype analysis to predict pharmacokinetics.
PURPOSE The purpose was to explore the relationships between irinotecan disposition and allelic variants of genes coding for… 
Highly Cited
2002
Highly Cited
2002
Current progress on esterases: from molecular structure to function.
This article reports on a symposium sponsored by the American Society for Pharmacology and Experimental Therapeutics and held at… 
Review
1998
Review
1998
The mammalian carboxylesterases: from molecules to functions.
Multiple carboxylesterases (EC 3.1.1.1) play an important role in the hydrolytic biotransformation of a vast number of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)