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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver.
- J. Horton, J. Goldstein, Michael S. Brown
- Biology, ChemistryThe Journal of clinical investigation
- 1 May 2002
TLDR
Regulation of the mevalonate pathway
- J. Goldstein, Michael S. Brown
- BiologyNature
- 1 February 1990
TLDR
A receptor-mediated pathway for cholesterol homeostasis.
- M. Brown, J. Goldstein
- BiologyScience
- 4 April 1986
TLDR
The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor
- Michael S. Brown, J. Goldstein
- MedicineCell
- 2 May 1997
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs.
- J. Ye, R. B. Rawson, J. Goldstein
- BiologyMolecular cell
- 1 December 2000
Protein Sensors for Membrane Sterols
- J. Goldstein, R. DeBose-Boyd, Michael S. Brown
- BiologyCell
- 13 January 2006
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
- J. Horton, N. Shah, J. Goldstein
- BiologyProceedings of the National Academy of Sciences…
- 25 September 2003
TLDR
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta.
- J. Repa, G. Liang, D. Mangelsdorf
- BiologyGenes & development
- 2000
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