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pepstatin

Known as: Ahpatinin C, Pepsin inhibitor S 735A, N-Isovaleryl-L-valyl-L-valyl-3-hydroxy-6-methyl-gamma-aminoheptanoyl-L-alanyl-3-hydroxy-6-methyl-gamma-aminoheptanoic Acid 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

AntimalarialsPepstatinsProtease Inhibitors

Papers overview

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Highly Cited
1992
Highly Cited
1992
Plasma membrane inositol 1,4,5-trisphosphate receptor of lymphocytes: selective enrichment in sialic acid and unique binding specificity.
The inositol 1,4,5-trisphosphate receptor (IP3R) associated with plasma membranes of lymphocytes differs in terminal sugar… 
Highly Cited
1989
Highly Cited
1989
Synthesis, purification, and active site mutagenesis of recombinant porcine pepsinogen.
Highly Cited
1985
Highly Cited
1985
Inhibition of aspartic proteases by pepstatin and 3-methylstatine derivatives of pepstatin. Evidence for collected-substrate enzyme inhibition.
The synthesis of 10 analogues of pepstatin modified so that statine is replaced by 4-amino-3-hydroxy-3,6-dimethylheptanoic acid… 
Highly Cited
1982
Highly Cited
1982
The effect of short-term and chronic immunosuppression on Theiler's virus demyelination
Highly Cited
1982
Highly Cited
1982
Conformational flexibility in the active sites of aspartyl proteinases revealed by a pepstatin fragment binding to penicillopepsin.
Crystals of the molecular complex between the esterified tripeptide fragment of pepstatin and the aspartyl proteinase… 
Highly Cited
1980
Highly Cited
1980
Differential effects of proteinase inhibitors and amines on the lysosomal and non-lysosomal pathways of protein degradation in isolated rat hepatocytes.
Highly Cited
1975
Highly Cited
1975
Isolation of pure and stable renin from hog kidney.
Highly Cited
1975
Highly Cited
1975
Proteolytic activity associated with human erythrocyte membranes. Self-digestion of isolated human erythrocyte membranes.
Highly Cited
1974
Highly Cited
1974
Role of individual cathepsins in lysosomal protein digestion as tested by specific inhibitors.
Highly Cited
1972
Highly Cited
1972
Inhibition of the Renin-Angiotensinogen Reaction by Pepstatin
Pepstatin, an N-acylated pentapeptide obtained from culture filtrates of actinomycetes and first characterized as an inhibitor of… 
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