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pepstatin

Known as: Ahpatinin C, Pepsin inhibitor S 735A, N-Isovaleryl-L-valyl-L-valyl-3-hydroxy-6-methyl-gamma-aminoheptanoyl-L-alanyl-3-hydroxy-6-methyl-gamma-aminoheptanoic Acid 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

AntimalarialsPepstatinsProtease Inhibitors

Papers overview

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2017
2017
Effect Unveils Inter-head Cooperativity and Strain-dependent ADP Release in Fast Skeletal Actomyosin
Amrinone is a bipyridine compound with characteristic effects on the force-velocity relationship of fast skeletal muscle… 
1986
1986
Pepstatin analogues as novel renin inhibitors.
Pepstatin analogues corresponding to the general formula A-X-Y-Sta-Ala-Sta-R were synthesized in solution phase. Various changes… 
1986
1986
Inhibition of cathepsin D by substrate analogues containing statine and by analogues of pepstatin.
Five new cathepsin D inhibitors were synthesized and tested as inhibitors of bovine cathepsin D. The compounds were derived by… 
Highly Cited
1985
Highly Cited
1985
Pepstatin-derived inhibitors of aspartic proteinases. A close look at an apparent transition-state analogue inhibitor.
1983
1983
Receptor-mediated introduction of pepstatin-asialofetuin conjugate into lysosomes of rat hepatocytes.
Pepstatin was linked through a carboxyl group to asialofetuin (PS-ASF). An analysis by separation of hepatocytes from… 
Highly Cited
1982
Highly Cited
1982
Conformational flexibility in the active sites of aspartyl proteinases revealed by a pepstatin fragment binding to penicillopepsin.
Crystals of the molecular complex between the esterified tripeptide fragment of pepstatin and the aspartyl proteinase… 
1975
1975
Pepstatin, an inhibitor of leukokinin formation and ascitic fluid accumulation.
Ascites fluid accumulation accompanying a mastocytoma or L1210 murine tumor is significantly retarded following the i.p. or s.c… 
1975
1975
Active and Passive Immunization Against Angiotensin II in the Rat and Rabbit: EVIDENCE FOR A NORMAL REGULATION OF THE RENIN-ANGIOTENSIN SYSTEM
Active or passive immunization has been used repeatedly as a tool in studies on the role of the renin-angiotensin system in the… 
1974
1974
Pepstatin inhibition of human renin. Kinetic studies and estimation of enzyme purity.
Abstract Pepstatin has been shown to be an extremely potent inhibitor of human renin (Ki = 1.3 x 10-10 m). Kinetic analyses by… 
Highly Cited
1972
Highly Cited
1972
The inhibition of tissue acid proteinases by pepstatin.