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Pepstatins

Known as: Pepstatins [Chemical/Ingredient] 
N-acylated oligopeptides isolated from culture filtrates of Actinomycetes, which act specifically to inhibit acid proteases such as pepsin and renin.
National Institutes of Health

Papers overview

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1999
1999
The promising strategy of gastric ulcer healing with perorally administered epidermal growth factor (EGF) is so far strongly… Expand
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Review
1993
Review
1993
 
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1990
1990
The separation of pepsin isoenzymes 1, 2, 3 and 5 (gastricsin) in human gastric juice was effected by chromatography on Mono Q… Expand
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1983
1983
1. N-Pepstatinyl-N'-dinitrophenyl-1,6-diaminohexane, a potential active-site-directed localization reagent for cathepsin D, was… Expand
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1982
1982
Lactoyl-pepstatin (an acylated tetrapeptide) is much more readily soluble in aqueous media than the more common isovaleryl- and… Expand
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1980
1980
Extracellular cathepsin D has been observed by various cytochemical methods at sites of tissue injury. However, the role of this… Expand
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1978
1978
1. Synthesis of several pepstatin A derivatives was performed with the aim of increasing water solubility without altering the… Expand
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1973
Highly Cited
1972
Highly Cited
1972
The inhibition of pepsin, cathepsin D and renin by pepstatins, pepstanone A and their partial peptides is described. A new method… Expand
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