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Pepstatins

Known as: Pepstatins [Chemical/Ingredient] 
N-acylated oligopeptides isolated from culture filtrates of Actinomycetes, which act specifically to inhibit acid proteases such as pepsin and renin.
National Institutes of Health

Related topics

Related topics

20 relations
In BloodProcess of secretionagonistsantagonists & inhibitors

Narrower (11)

JMV4463N-pepstatinyl-N'-dansyldiaminopropaneStreptomyces pepsin inhibitorhydroxypepstatin

Broader (1)

Protease Inhibitors

Papers overview

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1983
1983
Dinitrophenyl-pepstatins as active-site-directed localization reagents for cathepsin D.
1. N-Pepstatinyl-N'-dinitrophenyl-1,6-diaminohexane, a potential active-site-directed localization reagent for cathepsin D, was… 
1979
1979
Synthesis and antipepsin activities of peptides having a valine or valylvaline moiety at the N-terminus.
A series of peptides having a valine or valyvaline moiety at the N-terminus, 1-13, was prepared and their antipepsin activities… 
1975
1975
N-acylated derivatives of a peptide obtained by enzymatic degradation of pepstatins.
Sir: Naturally occurring pepstatins have been shown to possess two moles of an interesting amino acid, 4-amino-3-hydroxy-6… 
1975
1975
Enzymatic degradation of pepstatin A to a new tetrapeptide.
general structural formula can be shown as follows: R-L-valyl-L-valyl-4-amino-3-hydroxy6-methylheptanoyl-L-alanyl-4-amino3…