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ozagrel

Known as: 2-Propenoic acid, 3-(4-(1H-imidazol-1-ylmethyl)phenyl)-, (E)-, 3-(4-(1H-imidazol-1-ylmethyl)phenyl)-2-propenoic acid, 4-(1-imidazoylmethyl)cinnamic acid 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (4)

Enzyme InhibitorsFibrinolytic AgentsHistamine AntagonistsMethacrylates

Narrower (2)

OKY 046sodium ozagrel

Papers overview

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2013
2013
Ozagrel hydrochloride, a selective thromboxane A2 synthase inhibitor, alleviates liver injury induced by acetaminophen overdose in mice
BackgroundOverdosed acetaminophen (paracetamol, N-acetyl-p-aminophenol; APAP) causes severe liver injury. We examined the effects… 
2009
2009
A selective thromboxane A2 (TXA2) synthase inhibitor, ozagrel, attenuates lung injury and decreases monocyte chemoattractant protein-1 and interleukin-8 mRNA expression in oleic acid-induced lung…
This study examined the effect of ozagrel, a thromboxane A(2) synthase inhibitor, on the accumulation of leucocytes and chemokine… 
2007
2007
Wide therapeutic time window for fasudil neuroprotection against ischemia-induced delayed neuronal death in gerbils
2004
2004
Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid‐induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea‐pigs
An intravenous injection of oleic acid into animals can produce a lung injury with hypoxaemia and pulmonary vascular hyper… 
2003
2003
Endothelium-derived prostaglandin H2 evokes the stretch-induced contraction of rabbit pulmonary artery.
2000
2000
Participation of thromboxane A2 in the cough response in guinea‐pigs: antitussive effect of ozagrel
The purpose of this study was to investigate the involvement of thromboxane A2 (TXA2) in the cough response in a guinea‐pig cough… 
1999
1999
Effect of Ozagrel on Locomotor and Motor Coordination after Transient Cerebral Ischemia in Experimental Animal Models
The effect of ozagrel, a selective thromboxane A2 (TXA2) synthetase inhibitor, on the obstruction after cerebral ischemia… 
1997
1997
Thromboxane A2 synthetase inhibition suppresses cough induced by angiotensin converting enzyme inhibitors.
1995
1995
Prostaglandins and diabetic nephropathy.
Review
1994
Review
1994
[Research and development of ozagrel, a highly selective inhibitor of TXA2 synthase].
Highly selective inhibitors of thromboxane (TX) A2 synthase were noted as a therapeutic agent for ischemic heart diseases… 
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