oxidosqualene

Known as: squslene oxide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2017
051019752017

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2 relations

Broader (1)

Squalene
analogs & derivatives

Related mentions per year

Related mentions per year

1936-2019
19401960198020002020
oxidosqualene
Squalene
analogs & derivatives

Papers overview

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2010
2010
Cloning and characterization of oxidosqualene cyclases from Kalanchoe daigremontiana: enzymes catalyzing up to 10 rearrangement steps yielding friedelin and other triterpenoids.
The first committed step in triterpenoid biosynthesis is the cyclization of oxidosqualene to polycyclic alcohols or ketones C(30… (More)
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2004
2004
Differential expression of three oxidosqualene cyclase mRNAs in Glycyrrhiza glabra.
The cultured cells and intact plants of Glycyrrhiza glabra (Fabaceae) produce betulinic acid and oleanane-type triterpene… (More)
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2003
2003
Oxidosqualene cyclases from cell suspension cultures of Betula platyphylla var. japonica: molecular evolution of oxidosqualene cyclases in higher plants.
Betula platyphylla var. japonica is a rich source of triterpenoid as it contains dammarane type triterpenes in the leaves, and… (More)
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2002
2002
Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles.
Oxidosqualene cyclase of the yeast encoded by the ERG7 gene converts oxidosqualene to lanosterol, the first cyclic component of… (More)
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2001
2001
Potent anti-Trypanosoma cruzi activities of oxidosqualene cyclase inhibitors.
Trypanosoma cruzi is the protozoan agent that causes Chagas' disease, a major health problem in Latin America. Better drugs are… (More)
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2001
2001
A new class of oxidosqualene cyclases directs synthesis of antimicrobial phytoprotectants in monocots.
Many plants synthesize antimicrobial secondary metabolites as part of their normal program of growth and development, often… (More)
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2000
2000
Arabidopsis thaliana LUP1 converts oxidosqualene to multiple triterpene alcohols and a triterpene diol.
The Arabidopsis thaliana LUP1 gene encodes an enzyme that converts oxidosqualene to pentacyclic triterpenes. Lupeol and beta… (More)
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1999
1999
Two branches of the lupeol synthase gene in the molecular evolution of plant oxidosqualene cyclases.
Two new triterpene synthase cDNAs, named as OEW and TRW, were cloned from olive leaves (Olea europaea) and from dandelion roots… (More)
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Highly Cited
1998
Highly Cited
1998
Beta-amyrin synthase--cloning of oxidosqualene cyclase that catalyzes the formation of the most popular triterpene among higher plants.
Beta-amyrin, a typical pentacyclic triterpene having an oleanane skeleton, is one of the most commonly occuring triterpenes in… (More)
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1998
1998
29-Methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase.
Two pairs of isomers (18Z)- (8), (18E)-29-methylidene-2,3-oxidohexanorsqualene (21), and (18Z)- (31), (18E)-29-methylidene-2,3… (More)
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