otilonium bromide

Known as: N-diethylmethylammoniummethyl-p-(2-(N-octyloxy)benzoyl)aminobenzoate bromide, octylonium bromide 
 
National Institutes of Health

Papers overview

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2011
2011
BACKGROUND Otilonium bromide (OB) is a spasmolytic agent that blocks L-Type Calcium channels in human colonic smooth muscle… (More)
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2010
2010
BACKGROUND The mechanism of action of the spasmolytic compound otilonium bromide (OB) on human colonic motility is not understood… (More)
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2004
2004
The aim of this study is to evaluate in vitro the effect of otilonium bromide (OB) on the mechanical and electrical activities of… (More)
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Highly Cited
2004
Highly Cited
2004
To evaluate therapies available for the treatment of irritable bowel syndrome, and provide consensus recommendations for their… (More)
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2004
2004
Otilonium bromide (OB) is used as an intestinal antispasmodic. The mechanism of action of OB is not completely understood. As Ca… (More)
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2002
2002
BACKGROUND/OBJECTIVE In order to follow the most recent developments and recommendations in trial methodology for drug evaluation… (More)
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Review
1999
Review
1999
Experimental studies have shown that otilonium bromide (OB) inhibits both baseline and chemically or physically stimulated… (More)
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1998
1998
AIM To evaluate the efficacy of otilonium bromide, a spasmolytic agent, in the treatment of irritable bowel syndrome using modern… (More)
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1998
1998
The interaction of Otilonium bromide (OB) with binding sites for 63 different receptors and ion channels in appropriate… (More)
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1986
1986
This study was undertaken to evaluate (1) the colonic response to eating for a prolonged time in healthy subjects and patients… (More)
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