methyllycaconitine

 
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
Upon ligand binding at the subunit interfaces, the extracellular domain of the nicotinic acetylcholine receptor undergoes… (More)
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Highly Cited
2004
Highly Cited
2004
Pharmacological evaluation of nicotine-stimulated dopamine release from striatum has yielded data consistent with activation of a… (More)
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Highly Cited
2002
Highly Cited
2002
Neuronal nicotinic acetylcholine receptors (nAChRs) expressed on mesostriatal dopaminergic neurons are thought to mediate several… (More)
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Highly Cited
2001
Highly Cited
2001
Nicotinic acetylcholine receptors (nAChRs) on dopaminergic (DA) and GABAergic (Gaba) projection neurons of the substantia nigra… (More)
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Highly Cited
2001
Highly Cited
2001
Nicotinic acetylcholine receptor (nAChR) antagonists have been shown previously to decrease nicotine self-administration and… (More)
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Highly Cited
2000
Highly Cited
2000
Nicotinic acetylcholine receptors (nAChRs) are expressed in the hippocampus, and their functional roles are beginning to be… (More)
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Highly Cited
1999
Highly Cited
1999
Methyllycaconitine (MLA), a norditerpenoid alkaloid isolated from Delphinium seeds, is one of the most potent non-proteinacious… (More)
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Highly Cited
1996
Highly Cited
1996
1. The recently isolated compound methyllycaconitine (MLA) is a plant toxin which is a competitive inhibitor of nicotinic… (More)
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Highly Cited
1992
Highly Cited
1992
Methyllycaconitine, a toxin isolated from the seeds of Delphinium brownii, inhibited acetylcholine- and anatoxin-induced whole… (More)
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Highly Cited
1990
Highly Cited
1990
The ability of methyllycaconitine (MLA) to inhibit the binding of [125I]alpha-bungarotoxin to rat brain membranes, frog and human… (More)
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