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Nicotinic Antagonists

Known as: Nicotinic Antagonist, antagonist nicotinic, Nicotinic Cholinergic Antagonist 
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
In humans, tobacco withdrawal produces symptoms that contribute to the difficulty associated with smoking cessation. Nicotine… Expand
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Highly Cited
2007
Highly Cited
2007
Anxiolytic effects of nicotine have been documented in studies with rodents and humans. Understanding the neural basis of… Expand
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Highly Cited
2005
Highly Cited
2005
Rats were trained to self-administer nicotine on a fixed-ratio schedule of reinforcement. Infusion of the nicotinic antagonist… Expand
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Highly Cited
2005
Highly Cited
2005
Herein we describe a novel series of compounds from which varenicline (1, 6,7,8,9-tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3… Expand
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Highly Cited
2004
Highly Cited
2004
Almost all degenerative diseases of the CNS are associated with chronic inflammation. A central step in this process is the… Expand
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Highly Cited
2000
Highly Cited
2000
Neuronal nicotinic receptors are ligand-gated ion channels of the central and peripheral central nervous system that regulate… Expand
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Review
1998
Review
1998
Abstract Nicotinic cholinergic systems are involved with several important aspects of cognitive function including attention… Expand
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Highly Cited
1997
Highly Cited
1997
Catecholamine secretory vesicle core proteins (chromogranins) contain an activity that inhibits catecholamine release, but the… Expand
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Highly Cited
1994
Highly Cited
1994
Stimulation of the mesolimbic dopamine (DA) system is considered of major importance for the rewarding and dependence producing… Expand
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Highly Cited
1994
Highly Cited
1994
Microinfusions of the nicotinic antagonist dihydro-beta-erythroidine (DH beta E) were used to examine the role of the mesolimbic… Expand
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