Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells.

@article{Singh2013NicotinicAR,
  title={Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells.},
  author={Nagendra Surendra Singh and Rajib K. Paul and Anuradha Ramamoorthy and Marc C. Torjman and Ruin Moaddel and Michel Bernier and Irving W Wainer},
  journal={Cellular signalling},
  year={2013},
  volume={25 12},
  pages={2634-45}
}
Western blot analysis demonstrated that PC-12 cells express monomeric and dimeric forms of serine racemase (m-SR, d-SR) and that 1321N1 cells express m-SR. Quantitative RT-PCR and functional studies demonstrated that PC-12 cells express homomeric and heteromeric forms of nicotinic acetylcholine receptors (nAChR) while 1321N1 cells primarily express the α7-nAChR subtype. The effect of nAChR agonists and antagonists on SR activity and expression was examined by following concentration-dependent… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 27 references

W

L. Toll, N. T. Zaveri, W. E. Polgar, F. Jiang, T. V. Khroyan
Zhou, X.S. Xie, G.B. Stauber, M.R. Costello, F.M. Leslie, Neuropsychopharmacology 37 • 2012
View 13 Excerpts
Highly Influenced

T

C. Henneberger
Papouin, S.H. Oliet, D.A. Rusakov, Nature 463 • 2010
View 4 Excerpts
Highly Influenced

Eur

R. Moaddel, G. Abdrakhmanova, +8 authors I. W. Wainer
J. Pharmacol. 698 • 2013

J

P. Scholze, G. Koth, A. Orr-Urtreger, S. Huck
Neurochem. 121 • 2012

L

T. Papouin, L. Ladépéche, +4 authors L. Groc
Pollegioni, J.-P. Mothet, S.H.R. Oliet, Cell 150 • 2012
View 1 Excerpt

Curr

J. Jirásková-Vanícková, R. Ettrich, +4 authors J. Konvalinka
Drug Targets 12 • 2011
View 3 Excerpts

I

C. Vargas-Lopes, C. Madeira, S. A. Kahn
Albino do Couto, P. Bado, J.C. Houzel, J. De Miranda, M.S. de Freitas, S.T. Ferreira, R. Panizzutti, J. Neurochem. 116 • 2011
View 1 Excerpt

Brain Res

E. J. Gubbins, M. Gopalakrishnan, J. Li
1328 • 2010
View 3 Excerpts

FEBS Lett

V. N. Foltyn, M. Zehl, E. Dikopoltsev, O. N. Jensen, H. Wolosker
584 • 2010
View 1 Excerpt

Mol

L. Ning, H. Chen, M. Kunnimalaiyaan
Cancer Res. 8 • 2010
View 1 Excerpt

Similar Papers

Loading similar papers…