Skip to search formSkip to main contentSkip to account menu

methyl protodioscin

Known as: MPD cpd 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

DiosgeninSaponins
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Methyl Protodioscin, a Steroidal Saponin, Inhibits Neointima Formation in Vitro and in Vivo.
Restenosis (or neointimal hyperplasia) remains a clinical limitation of percutaneous coronary angioplasty. Abnormal proliferation… 
2015
2015
Natural compound methyl protodioscin protects against intestinal inflammation through modulation of intestinal immune responses
Dioscoreaceae, a kind of yam plant, has been recommended for treatment of chronic inflammatory conditions. However, the… 
2015
2015
Methyl Protodioscin from the Roots of Asparagus cochinchinensis Attenuates Airway Inflammation by Inhibiting Cytokine Production
The present study was designed to find pharmacologically active compound against airway inflammation from the roots of Asparagus… 
2014
2014
Methyl protodioscin induces G2/M cell cycle arrest and apoptosis in A549 human lung cancer cells
Background: Methyl protodioscin (MPD) is a furostanol bisglycoside with antitumor properties. It has been shown to reduce… 
2010
2010
Pharmacokinetics of methyl protodioscin in rats.
Methyl protodioscin (MPD), a natural furostanol saponin, showed distinct antitumor activity and is distributed in many… 
2008
2008
Development and validation of a liquid chromatography/tandem mass spectrometry assay for the quantification of methyl protodioscin in rat plasma: application to a pharmacokinetic study.
A high performance liquid chromatography/tandem mass spectrometry assay was first developed and validated for the quantification… 
Highly Cited
2007
Highly Cited
2007
Characterization of steroidal saponins in crude extract from Dioscorea nipponica Makino by liquid chromatography tandem multi-stage mass spectrometry.
2006
2006
Facile conversion of spirostan saponin into furostan saponin: synthesis of methyl protodioscin and its 26-thio-analogue.
[reaction: see text] A facile approach for the conversion of a spirostan saponin into its furostan counterpart, as illustrated by… 
2006
2006
Structural identification of methyl protodioscin metabolites in rats’ urine and their antiproliferative activities against human tumor cell lines
Highly Cited
2005
Highly Cited
2005
Methyl protodioscin induces G2/M arrest and apoptosis in K562 cells with the hyperpolarization of mitochondria.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)