metabotropic glutamate receptor 5

Known as: Receptor, Metabotropic Glutamate 5, mGluR5 Protein, Receptor 5, Metabotropic Glutamate 
Metabotropic glutamate receptor 5 (1212 aa, ~132 kDa) is encoded by the human GRM5 gene. This protein plays a role in both glutamate binding and… (More)

Topic mentions per year

Topic mentions per year

1994-2018
020406019942018

Papers overview

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Highly Cited
2014
Highly Cited
2014
Metabotropic glutamate receptors are class C G-protein-coupled receptors which respond to the neurotransmitter glutamate… (More)
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Highly Cited
2013
Highly Cited
2013
Soluble amyloid-β oligomers (Aβo) trigger Alzheimer's disease (AD) pathophysiology and bind with high affinity to cellular prion… (More)
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Highly Cited
2011
Highly Cited
2011
OBJECTIVE To report the metabotropic glutamate receptor 5 (mGluR5) as the autoantigen of antibodies from 2 patients with Hodgkin… (More)
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Highly Cited
2009
Highly Cited
2009
Accumulating evidence suggests that metabotropic glutamate receptors (mGluRs) are involved in both cocaine reinforcement and the… (More)
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2007
2007
Metabotropic glutamate receptors (mGluRs) and Homer proteins play critical roles in neuronal functions including plasticity… (More)
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Highly Cited
2005
Highly Cited
2005
Group I metabotropic glutamate receptors (mGluRs) increase cellular levels of inositol-1,4,5-triphosphate (IP3) and thereby… (More)
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Highly Cited
2001
Highly Cited
2001
The activation of group I metabotropic glutamate receptors (mGluRs) produces a variety of actions that lead to alterations in… (More)
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Highly Cited
2000
Highly Cited
2000
The subthalamic nucleus (STN) is a key nucleus in the basal ganglia motor circuit that provides the major glutamatergic… (More)
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Highly Cited
2000
Highly Cited
2000
Recently, selective and systemically active antagonists for the metabotropic glutamate 5 receptor (mGlu(5)) were discovered, and… (More)
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Highly Cited
1997
Highly Cited
1997
Class I metabotropic glutamate receptors (mGluRs) have been postulated to play a role in synaptic plasticity. To test the… (More)
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