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metabotropic glutamate receptor 5

Known as: Receptor, Metabotropic Glutamate 5, mGluR5 Protein, Receptor 5, Metabotropic Glutamate 
Metabotropic glutamate receptor 5 (1212 aa, ~132 kDa) is encoded by the human GRM5 gene. This protein plays a role in both glutamate binding and… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Metabotropic glutamate receptors are class C G-protein-coupled receptors which respond to the neurotransmitter glutamate… Expand
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Highly Cited
2013
Highly Cited
2013
Soluble amyloid-β oligomers (Aβo) trigger Alzheimer's disease (AD) pathophysiology and bind with high affinity to cellular prion… Expand
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Highly Cited
2011
Highly Cited
2011
Objective: To report the metabotropic glutamate receptor 5 (mGluR5) as the autoantigen of antibodies from 2 patients with Hodgkin… Expand
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Highly Cited
2009
Highly Cited
2009
Accumulating evidence suggests that metabotropic glutamate receptors (mGluRs) are involved in both cocaine reinforcement and the… Expand
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Highly Cited
2005
Highly Cited
2005
Group I metabotropic glutamate receptors (mGluRs) increase cellular levels of inositol-1,4,5-triphosphate (IP3) and thereby… Expand
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Highly Cited
2001
Highly Cited
2001
Medium spiny neurons were recorded from striatal slices obtained from mice lacking the group I metabotropic glutamate receptor… Expand
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Highly Cited
2000
Highly Cited
2000
The subthalamic nucleus (STN) is a key nucleus in the basal ganglia motor circuit that provides the major glutamatergic… Expand
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Highly Cited
1997
Highly Cited
1997
Class I metabotropic glutamate receptors (mGluRs) have been postulated to play a role in synaptic plasticity. To test the… Expand
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Highly Cited
1996
Highly Cited
1996
The sequences of the metabotropic glutamate receptors (mGluRs) show little homology with other members of the G protein-coupled… Expand
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Highly Cited
1994
Highly Cited
1994
Metabotropic glutamate receptors (mGluRs) couple the actions of glutamate to intracellular second messenger systems through G… Expand
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