GRM5 wt Allele

Known as: MGLUR5, Protein Phosphatase 1, Regulatory Subunit 86 Gene, Glutamate Receptor, Metabotropic, 5 Gene 
Human GRM5 wild-type allele is located within 11q14.2-q14.3 and is approximately 558 kb in length. This allele, which encodes metabotropic glutamate… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Fragile X syndrome (FXS) is the most common form of inherited intellectual disability. Previous studies have implicated mGlu5 in… (More)
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Review
2007
Review
2007
Adenosine A2A receptors are highly enriched in the basal ganglia system. They are predominantly expressed in enkephalin… (More)
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Review
2005
Review
2005
Anxiety and stress disorders are the most commonly occurring of all mental illnesses, and current treatments are less than… (More)
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Highly Cited
2005
Highly Cited
2005
Fenobam [N-(3-chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazole-2-yl)urea] is an atypical anxiolytic agent with unknown… (More)
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Highly Cited
2004
Highly Cited
2004
Pharmacological manipulation of N-methyl-D-aspartate (NMDA) receptors may be critical for the treatment of many neurological and… (More)
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Highly Cited
2003
Highly Cited
2003
2-Methyl-6-(phenylethynyl)pyridine (3), a potent noncompetitive mGlu5 receptor antagonist widely used to characterize the… (More)
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Highly Cited
2002
Highly Cited
2002
The physiological meaning of the coexpression of adenosine A2A receptors and group I metabotropic glutamate receptors in gamma… (More)
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Highly Cited
2001
Highly Cited
2001
Both ionotropic and metabotropic glutamate receptors (mGluRs) are involved in the behavioral effects of pyschostimulants; however… (More)
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Highly Cited
1999
Highly Cited
1999
In the present paper we describe 2-methyl-6-(phenylethynyl)-pyridine (MPEP) as a potent, selective and systemically active… (More)
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Highly Cited
1997
Highly Cited
1997
The group I specific metabotropic glutamate (mGlu) receptor agonist (RS)-3,5-dihydroxyphenylglycine (DHPG) (100 microM, 10 min… (More)
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