membrane depolarization

The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive… (More)
National Institutes of Health

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membrane depolarization during atrial cardiac muscle cell action potentialmembrane depolarization during ventricular cardiac muscle cell action potentialmitochondrial depolarization

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Highly Cited
2007
Highly Cited
2007
Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation.
During neuronal activity, extracellular potassium concentration ([K+]out) becomes elevated and, if uncorrected, causes neuronal… (More)
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Highly Cited
2003
Highly Cited
2003
Correlation of daptomycin bactericidal activity and membrane depolarization in Staphylococcus aureus.
The objective of this study was to further elucidate the role of membrane potential in the mechanism of action of daptomycin, a… (More)
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Highly Cited
2002
Highly Cited
2002
TRPM4 Is a Ca2+-Activated Nonselective Cation Channel Mediating Cell Membrane Depolarization
Calcium-activated nonselective (CAN) cation channels are expressed in various excitable and nonexcitable cells supporting… (More)
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Highly Cited
1997
Highly Cited
1997
Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria
Mitochondrial physiology is disrupted in either apoptosis or necrosis. Here, we report that a wide variety of apoptotic and… (More)
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Highly Cited
1996
Highly Cited
1996
Membrane depolarization induces calcium-dependent secretion of tissue plasminogen activator.
Tissue plasminogen activator (tPA), a serine protease that converts inactive plasminogen to active plasmin, is produced in the… (More)
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Highly Cited
1995
Highly Cited
1995
GABA and glutamate depolarize cortical progenitor cells and inhibit DNA synthesis
We have found that, during the early stages of cortical neurogenesis, both GABA and glutamate depolarize cells in the ventricular… (More)
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Highly Cited
1990
Highly Cited
1990
Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB.
The mechanism by which the calcium influx signal, triggered by membrane depolarization, is transduced to the nucleus to activate… (More)
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Highly Cited
1988
Highly Cited
1988
A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization.
Egr-1 is an early growth response gene that displays fos-like induction kinetics in fibroblasts, epithelial cells, and… (More)
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Highly Cited
1984
Highly Cited
1984
Pressure-dependent membrane depolarization in cat middle cerebral artery.
This study was undertaken to examine the effect of increasing transmural pressure on membrane electrical properties of cat middle… (More)
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Highly Cited
1981
Highly Cited
1981
Thresholds in cerebral ischemia - the ischemic penumbra.
COMPLETE ARREST of the cerebral circulation leads within seconds to cessation of neuronal electrical activity and within a few… (More)
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