mitochondrial depolarization

Known as: mitochondria depolarization, mitochondrial depolarisation, mitochondrion depolarization 
The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level. [Wikipedia:Depolarization… (More)
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
The PARKIN ubiquitin ligase (also known as PARK2) and its regulatory kinase PINK1 (also known as PARK6), often mutated in… (More)
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Highly Cited
2012
Highly Cited
2012
Reactive oxygen species (ROS) have been implicated as a signal for general autophagy. Both mitochondrial-produced and exogenous… (More)
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Highly Cited
2011
Highly Cited
2011
Upon mitochondrial depolarization, Parkin, a Parkinson disease-related E3 ubiquitin ligase, translocates from the cytosol to… (More)
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Highly Cited
2011
Highly Cited
2011
Recent studies delineate a pathway involving familial Parkinson's disease (PD)-related proteins PINK1 and Parkin, in which PINK1… (More)
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Highly Cited
2010
Highly Cited
2010
Parkinson's disease (PD) is a prevalent neurodegenerative disorder. Recent identification of genes linked to familial forms of PD… (More)
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Highly Cited
2010
Highly Cited
2010
Mitochondria sustain damage with aging, and the resulting mitochondrial dysfunction has been implicated in a number of diseases… (More)
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Highly Cited
2004
Highly Cited
2004
Beta-amyloid (betaA) peptide is strongly implicated in the neurodegeneration underlying Alzheimer's disease, but the mechanisms… (More)
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Highly Cited
1999
Highly Cited
1999
Cytochrome c is released from mitochondria into the cytosol in cells undergoing apoptosis. The temporal relationship between… (More)
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Highly Cited
1999
Highly Cited
1999
Huntington disease (HD) is a genetically dominant condition caused by expanded CAG repeats coding for glutamine in the HD gene… (More)
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Highly Cited
1999
Highly Cited
1999
Mitochondria are sites of cellular energy production but may also influence life and death decisions by initiating or inhibiting… (More)
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