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mitochondrial depolarization

Known as: mitochondria depolarization, mitochondrial depolarisation, mitochondrion depolarization 
The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level. [Wikipedia:Depolarization… 
National Institutes of Health

Related topics

Related topics

2 relations
Mitochondria

Broader (1)

membrane depolarization

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor
Highly Cited
2015
Highly Cited
2015
PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis.
Although aging is a known risk factor for idiopathic pulmonary fibrosis (IPF), the pathogenic mechanisms that underlie the… 
Highly Cited
2012
Highly Cited
2012
ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy
Reactive oxygen species (ROS) have been implicated as a signal for general autophagy. Both mitochondrial-produced and exogenous… 
Highly Cited
2011
Highly Cited
2011
Mitochondrial Fission Contributes to Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle
ABSTRACT Mitochondrial dysfunction in skeletal muscle has been implicated in the development of insulin resistance and type 2… 
Highly Cited
2011
Highly Cited
2011
Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane*♦
Upon mitochondrial depolarization, Parkin, a Parkinson disease-related E3 ubiquitin ligase, translocates from the cytosol to… 
Highly Cited
2011
Highly Cited
2011
In vitro comparison of the photothermal anticancer activity of graphene nanoparticles and carbon nanotubes.
Highly Cited
2010
Highly Cited
2010
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
Defective mitochondrial quality control is shown to be a mechanism for neurodegeneration in some forms of Parkinson's disease. 
Highly Cited
2010
Highly Cited
2010
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
Mitochondria sustain damage with aging, and the resulting mitochondrial dysfunction has been implicated in a number of diseases… 
Highly Cited
2003
Highly Cited
2003
Coenzyme Q10 Prevents Apoptosis by Inhibiting Mitochondrial Depolarization Independently of Its Free Radical Scavenging Property*
The permeability transition pore (PTP) is a mitochondrial channel whose opening causes the mitochondrial membrane potential… 
Highly Cited
1999
Highly Cited
1999
Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization
Huntington disease (HD) is a genetically dominant condition caused by expanded CAG repeats coding for glutamine in the HD gene… 
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