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Stereoselective muscarinic acetylcholine and opiate receptiors in human phagocytic leukocytes.
Human granulocytes and monocytes exhibited stereospecific, high-affinity binding to 3-quinuclidinyl benzilate and dihydromorphine, specific ligands for the muscarinic cholinergic and opiate receptors respectively, which indicates that the affinity of the l -isomer is approximately 10 times that of the d-isomer. Expand
Effect of Chlorpromazine on Phosphorylation of Brain Mitochondria.∗
  • L. Abood
  • Biology, Medicine
  • Proceedings of the Society for Experimental…
  • 1 April 1955
Summary Chlorpromazine uncoupled the oxidative phosphorylation of brain mitochondria and inhibited cytochrome oxidase in concentrations not affecting overall oxidation. Since the drug inhibits theExpand
Structure-activity studies of carbamate and other esters: Agonists and antagonists to nicotine
A number of aromatic, cycloalkyl, and heterocyclic carbamic acid esters, thiocarbamic acid esters, and carboxylic acid esters of di- and trial-kylaminoalkyl and heterocyclic amino alcohols have beenExpand
Mechanism of Inhibition of Glycogen Synthesis by Endotoxins of Salmonella aertrycke and Type I Meningococcus.∗
  • E. Kun, L. Abood
  • Chemistry, Medicine
  • Proceedings of the Society for Experimental…
  • 1 July 1949
Summary In vivo and in vitro experiments indicated that the inhibition of pyruvate oxidation occurred in animals injected with bacterial endotoxins. The inhibitory factor was probably identical withExpand
Comparative study of blood ceruloplasmin in schizophrenia and other disorders.
Findings on the ceruloplasmin activity of serum from patients with schizophrenia and a variety of other disorders are reported; and the technique used, although similar to Akerfeldt's, appears to be somewhat simpler and subject to fewer errors. Expand
Breakdown of proteins and lipids during glucose-free perfusion of the cat's brain.
  • L. Abood, A. Geiger
  • Chemistry, Medicine
  • The American journal of physiology
  • 1 September 1955
Chemical requirements of vasopressins for barrel rotation convulsions and reversal by oxytocin
It was concluded that although the peptide could be acting by vasoconstricting blood arterioles and capillaries in the brain, it may also be exerting a direct excitatory action on neurons. Expand