loracarbef

Known as: loracarbef [Chemical/Ingredient], (6R, 7S)-7-[(R)-2-Amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, Monohydrate, 1-Azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((aminophenylacetyl)amino)-3-chloro-8-oxo-, (6R-(6alpha,7beta(R*)))- 
A semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic derived from cephasporium. The bactericidal… (More)
National Institutes of Health

Related topics

Related topics

17 relations

Broader (1)

Anti-Bacterial Agents
ArthropathyBacterial InfectionsBone Diseases, InfectiousCephalosporins
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Narrower (5)

CarbacLY 163892LorabidLorafem
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Papers overview

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2003
2003
Serologically documented loracarbef (Lorabid)-induced immune thrombocytopenia.
We report here the first case of severe immune thrombocytopenia induced by a second-generation cephalosporin antibiotic… (More)
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Highly Cited
1999
Highly Cited
1999
Susceptibilities of Streptococcus pneumoniae and Haemophilus influenzae to 10 oral antimicrobial agents based on pharmacodynamic parameters: 1997 U.S. Surveillance study.
The susceptibilities of Streptococcus pneumoniae (1,476 strains) and untypeable Haemophilus influenzae (1,676 strains) to various… (More)
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Highly Cited
1996
Highly Cited
1996
Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solvents
Through sequential generations of random mutagenesis and screening, we have directed the evolution of an esterase for… (More)
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Highly Cited
1996
Highly Cited
1996
Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995: results of a 30-center national surveillance study.
A total of 1,527 clinically significant outpatient isolates of Streptococcus pneumoniae were prospectively collected in 30… (More)
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Review
1996
Review
1996
Comparison of cefprozil, cefpodoxime proxetil, loracarbef, cefixime, and ceftibuten.
OBJECTIVE To discuss the pharmacokinetics, spectrum of activity, clinical trials, and adverse effects of cefprozil, cefpodoxime… (More)
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1994
1994
Effect of loracarbef and amoxicillin on the oropharyngeal and intestinal microflora of patients with bronchitis.
The effect on the oropharyngeal and intestinal microflora and the efficacy and tolerance of loracarbef (200 mg b.i.d. for 7 days… (More)
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1994
1994
Mechanism and Kinetics of Transcellular Transport of a New β-Lactam Antibiotic Loracarbef Across an Intestinal Epithelial Membrane Model System (Caco-2)
Various processes involved in the transcellular transport (TT) of loracarbef (LOR) were studied in the Caco-2 cell monolayer, a… (More)
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1993
1993
General pharmacology of loracarbef in animals.
Loracarbef ((6R, 7S)-7-[(R)-2-amino-2-phenyl-acetamido]-3-chloro-8-oxo-1- azabicyclo [4.2.0]oct-2-ene-2-carboxylic acid… (More)
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1992
1992
Loracarbef (LY 163892) vs amoxicillin/clavulanate in bacterial maxillary sinusitis.
Loracarbef (LY 163892), a beta-lactam antibiotic (carbacephem), was compared with amoxicillin/clavulanate potassium in a 10-day… (More)
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1990
1990
Loracarbef concentrations in middle ear fluid.
Loracarbef concentrations in plasma and middle ear fluid (MEF) were measured in specimens obtained approximately 2 h after doses… (More)
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