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Infections with Cryptococcus neoformans in the acquired immunodeficiency syndrome.
TLDR
It is concluded that the addition of flucytosine to amphotericin neither enhances survival nor prevents relapse, but long-term suppressive therapy appears to benefit these patients. Expand
Antibiotic prescribing for children with colds, upper respiratory tract infections, and bronchitis.
TLDR
Antibiotic prescribing for children diagnosed as having colds, URIs, and bronchitis, conditions that typically do not benefit from antibiotics, represents a substantial proportion of total antibiotic prescriptions to children in the United States each year. Expand
Laboratory medicine in Africa: a barrier to effective health care.
TLDR
The barriers to implementing consistent testing within this region are explored and the need for a more comprehensive approach to the diagnosis of infectious diseases is illustrated, with an emphasis on making laboratory testing a higher priority is illustrated. Expand
Principles of appropriate antibiotic use for acute pharyngitis in adults: background.
The following principles of appropriate antibiotic use for adults with acute pharyngitis apply to immunocompetent adults without complicated comorbid conditions, such as chronic lung or heartExpand
A comparison of amphotericin B alone and combined with flucytosine in the treatment of cryptoccal meningitis.
TLDR
It is concluded that combined flucytosine-amphoericin B therapy is the regimen of choice in cryptococcal meningitis. Expand
Toxoplasmosis of the central nervous system in the acquired immunodeficiency syndrome.
TLDR
Toxoplasmosis occurs in advanced stages of human immunodeficiency virus infection, and the absence of antitoxoplasma antibodies on immunofluorescence assay does not exclude the diagnosis. Expand
Excessive antibiotic use for acute respiratory infections in the United States.
TLDR
The amount and cost of excessive antibiotic use for acute respiratory infections by primary care physicians are substantial and potential target rates for antibiotic treatment of selected conditions are established. Expand
Antibiotic prescribing for adults with colds, upper respiratory tract infections, and bronchitis by ambulatory care physicians.
TLDR
Although antibiotics have little or no benefit for colds, upper respiratory tract infections, or bronchitis, these conditions account for a sizable proportion of total antibiotic prescriptions for adults by office-based physicians in the United States. Expand
Outcomes of cryptococcal meningitis in Uganda before and after the availability of highly active antiretroviral therapy.
TLDR
Significant CM-associated mortality persists, despite the administration of amphotericin B and HIV therapy, because of the high mortality rate before receipt of HAART and because of immune reconstitution inflammatory syndrome-related complications after HAART initiation. Expand
Spread of Streptococcus pneumoniae in families. I. Carriage rates and distribution of types.
TLDR
Findings included the importance of pharyngeal rather than of nasal sampling in adults, the greater sensitivity of mouse inoculation compared with direct streaking of blood agar plates, and the superiority of the Quellung reaction with omniserum over the optochin disk as a means of identification of S. pneumoniae. Expand
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