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inhibitor-of-apoptosis protein

Known as: Inhibitor of Apoptosis Protein, IAP Repeat Containing Proteins, Apoptosis Proteins Inhibitor 
A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they… 
National Institutes of Health

Papers overview

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Review
2006
Review
2006
Survivin is an inhibitor of apoptosis protein (IAP) expressed in a large number of adult malignancies. Its expression levels… 
Highly Cited
2005
Highly Cited
2005
The inhibitor of apoptosis protein (IAP) survivin is overexpressed in many tumors but is absent in most normal adult tissues. We… 
Highly Cited
2004
Highly Cited
2004
Cellular inhibitor of apoptosis protein 1 (c-IAP1) can regulate apoptosis through its interaction with downstream TNF receptor… 
Highly Cited
2004
Highly Cited
2004
Intramitochondrial serine protease activity of Omi/HtrA2 is required for caspase-independent cell death of human neutrophils 
2003
2003
We have previously shown that the clinically relevant polyamine analog N1,N11-diethylnorspermine (DENSPM) causes rapid apoptosis… 
Highly Cited
2002
Highly Cited
2002
Inhibitor of apoptosis proteins (IAPs) provide a critical barrier to inappropriate apoptotic cell death through direct binding… 
Highly Cited
1999
Highly Cited
1999
Survivin, a cell-death inhibitor, localizes to the spindles of mitotic cells, and its absence causes both a failure in cell…