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inhibitor-of-apoptosis protein

Known as: Inhibitor of Apoptosis Protein, IAP Repeat Containing Proteins, Apoptosis Proteins Inhibitor 
A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they… Expand
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Akt negatively regulates apoptotic pathways at a premitochondrial level through phosphorylation and modulation of proteins such… Expand
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Review
2004
Review
2004
The inhibitor of apoptosis proteins (IAPs) are a family of antiapoptotic proteins that bind and inhibit caspases 3, 7, and/or 9… Expand
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Highly Cited
2002
Highly Cited
2002
To identify human proteins that bind to the Smac and caspase-9 binding pocket on the baculoviral inhibitor of apoptosis protein… Expand
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Highly Cited
2002
Highly Cited
2002
Inhibitor of apoptosis (IAP) proteins inhibit caspases, a function counteracted by IAP antagonists, insect Grim, HID, and Reaper… Expand
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Highly Cited
2001
Highly Cited
2001
The inhibitor of apoptosis (IAP) family of anti-apoptotic proteins regulate programmed cell death and/or apoptosis. One such… Expand
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Highly Cited
2001
Highly Cited
2001
Human protein C is a natural anticoagulant factor, and a recombinant activated form of the molecule (rhAPC) is completing… Expand
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Highly Cited
2001
Highly Cited
2001
X-linked inhibitor-of-apoptosis protein (XIAP) interacts with caspase-9 and inhibits its activity, whereas Smac (also known as… Expand
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Highly Cited
1998
Highly Cited
1998
Survivin is a member of the inhibitor of apoptosis protein (IAP) family. We investigated the antiapoptotic mechanism of Survivin… Expand
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Highly Cited
1998
Highly Cited
1998
The inhibitor of apoptosis proteins (IAPs) constitute an evolutionarily conserved family of homologous proteins that suppress… Expand
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Highly Cited
1995
Highly Cited
1995
The 75 kDa tumor necrosis factor receptor (TNFR2) transduces extracellular signals via receptor-associated cytoplasmic proteins… Expand
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