inhibitor-of-apoptosis protein

Known as: Inhibitor of Apoptosis Protein, IAP Repeat Containing Proteins, Apoptosis Proteins Inhibitor 
A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
020406019952017

Papers overview

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Highly Cited
2004
Highly Cited
2004
Akt negatively regulates apoptotic pathways at a premitochondrial level through phosphorylation and modulation of proteins such… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE Inhibitor of apoptosis (IAP) family proteins are suppressors of apoptosis that have been implicated in apoptosis… (More)
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Highly Cited
2002
Highly Cited
2002
To identify human proteins that bind to the Smac and caspase-9 binding pocket on the baculoviral inhibitor of apoptosis protein… (More)
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Highly Cited
2002
Highly Cited
2002
Inhibitor of apoptosis (IAP) proteins inhibit caspases, a function counteracted by IAP antagonists, insect Grim, HID, and Reaper… (More)
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Highly Cited
2001
Highly Cited
2001
A novel human inhibitor of apoptosis protein (IAP) family member termed Livin was identified, containing a single baculoviral IAP… (More)
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Highly Cited
2001
Highly Cited
2001
The inhibitor of apoptosis (IAP) family of anti-apoptotic proteins regulate programmed cell death and/or apoptosis. One such… (More)
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Highly Cited
2001
Highly Cited
2001
X-linked inhibitor-of-apoptosis protein (XIAP) interacts with caspase-9 and inhibits its activity, whereas Smac (also known as… (More)
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Highly Cited
1998
Highly Cited
1998
Survivin is a member of the inhibitor of apoptosis protein (IAP) family. We investigated the antiapoptotic mechanism of Survivin… (More)
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Highly Cited
1997
Highly Cited
1997
IAPs comprise a family of inhibitors of apoptosis found in viruses and animals. In vivo binding studies demonstrated that both… (More)
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Highly Cited
1995
Highly Cited
1995
The 75 kDa tumor necrosis factor receptor (TNFR2) transduces extracellular signals via receptor-associated cytoplasmic proteins… (More)
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