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Caspase Inhibitors

Known as: Caspase Blockers, Caspase Inhibitor, Blockers, Caspase 
Any substance that inhibits a caspase-family protease. Caspases play a key role in apoptosis as well as in inflammation and immune regulation… 
National Institutes of Health

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Ac-AAVALLPAVLLALLAPYVAD-CHOCM 269CV 1013IDN 1529
Caspase Activation InhibitorsIn Bloodaspects of radiation effectschemical synthesis

Papers overview

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2017
2017
This information is current as Induced Cutaneous Inflammation − and Apoptotic Keratinocytes in Ultraviolet-B Anti-Inflammatory Role of Langerhans Cells
2014
2014
Cryptotanshinone Induces Apoptosis of HL-60 Cells via Mitochondrial Pathway
Purpose : To test the effect of Cryptotanshinone (CPT), a natural  compound isolated from the plant Salvia miltiorrhiza Bunge, on… 
2014
2014
Identification of active caspases using affinity-based probes.
Small-molecule inhibitors of caspases can be modified with moieties such as biotin or fluorescent molecules. After the inhibitor… 
2013
2013
activation of caspase-3 in neutrophils Granulocyte colony-stimulating factor inhibits the mitochondria-dependent
http://bloodjournal.hematologylibrary.org/content/99/2/672.full.html Updated information and services can be found at: (973… 
2011
2011
Matador and the Regulation of cyclin E1 in Normal Human Placental Development and Placental Pathology
Preeclampsia and molar pregnancy are two devastating placental pathologies characterized by an immature proliferative trophoblast… 
Review
2009
Review
2009
Cancer Therapy : Preclinical The Monoclonal Antibody nBT 062 Conjugated to Cytotoxic Maytansinoids Has Selective Cytotoxicity Against CD 138-Positive Multiple Myeloma Cells In vitro and In vivo
Purpose: We investigated the antitumor effect of murine/human chimeric CD138specific monoclonal antibody nBT062 conjugated with… 
Review
2007
Review
2007
OSU-03012 stimulates PERK-dependent increases in HSP 70 expression , attenuating its lethal actions in transformed cells
We have further defined mechanism(s) by which OSU-03012 (OSU), a derivative of the COX2 inhibitor Celecoxib but lacking COX2… 
2002
2002
Combretastatin-A 4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly ( ADP-ribose ) Polymerase Cleavage 1
We have previously reported that combretastatin-A4 prodrug (CA4P), an antitubulin/antiangiogenic agent isolated from the South… 
2002
2002
Inhibition of Protein Synthesis in Apoptosis : Differential Requirements by the Tumor Necrosis Factor Family and a DNA-damaging Agent for Caspases and the Double-stranded RNA-dependent Protein Kinase…
Exposure of mammalian cells to agents that induce apoptosis results in a rapid and substantial inhibition of protein synthesis… 
2001
2001
Mac-1 ( CD 11 b / CD 18 ) and intercellular adhesion molecule-1 in ischemia-reperfusion injury of rat liver
AKIRA KOBAYASHI,1 HIROSHI IMAMURA,1 MITSUAKI ISOBE,2 YUTAKA MATSUYAMA,3 JUNPEI SOEDA,1 KOTARO MATSUNAGA,4 AND SEIJI KAWASAKI1…