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BIRC2 protein, human

Known as: HIAP2, C-IAP1, Baculoviral IAP Repeat-Containing Protein 2 
Baculoviral IAP repeat-containing protein 2 (618 aa, ~70 kDa) is encoded by the human BIRC2 gene. This protein plays a role in the regulation of… 
National Institutes of Health

Related topics

Related topics

15 relations
ApoptosisApoptosis InhibitorBIR DomainBIRC2 gene

Broader (2)

inhibitor-of-apoptosis proteinubiquitin-protein ligase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Aerobic exercise training induces an anti-apoptotic milieu in myocardial tissue
Abstract —This study evaluated modulators of apoptosis in the myocardium of rats subjected to exercise training. Rats were… 
Highly Cited
2007
Highly Cited
2007
Association of cooking oil fumes exposure with lung cancer: involvement of inhibitor of apoptosis proteins in cell survival and proliferation in vitro.
Highly Cited
2005
Highly Cited
2005
Apoptosis induction by a novel retinoid-related molecule requires nuclear factor-kappaB activation.
Nuclear factor-kappaB (NF-kappaB) activation has been shown to be both antiapoptotic and proapoptotic depending on the stimulus… 
2005
2005
Enhancement of Sensitivity to Tumor Necrosis Factor α in Non–Small Cell Lung Cancer Cells with Acquired Resistance to Gefitinib
Tumor cells that have acquired resistance to gefitinib through continuous drug administration may complicate future treatment. To… 
Highly Cited
2004
Highly Cited
2004
Translation of cellular inhibitor of apoptosis protein 1 (c-IAP1) mRNA is IRES mediated and regulated during cell stress.
Cellular inhibitor of apoptosis protein 1 (c-IAP1) can regulate apoptosis through its interaction with downstream TNF receptor… 
2004
2004
Casein Kinase I Attenuates Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Induced Apoptosis by Regulating the Recruitment of Fas-Associated Death Domain and Procaspase-8 to the Death…
Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) induces apoptosis in a wide variety of malignant cell lines, in… 
Highly Cited
2003
Highly Cited
2003
A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha.
NEMO (NF-kappaB essential modifier)/IKKgamma (IkappaB kinase-gamma) is required for the activation of the IkappaB kinase complex… 
Highly Cited
2003
Highly Cited
2003
Inhibition of NF- (cid:1) B Sensitizes A431 Cells to Epidermal Growth Factor-induced Apoptosis, whereas Its Activation by Ectopic Expression of RelA Confers Resistance*
Epidermal growth factor (EGF) is a well known mitogen, but it paradoxically induces apoptosis in cells that overexpress its… 
2002
2002
Induction of human inhibitor of apoptosis protein‐2 by shear stress in endothelial cells
Highly Cited
2001
Highly Cited
2001
c-IAP1 Is Cleaved by Caspases to Produce a Proapoptotic C-terminal Fragment*
Although human c-IAP1 and c-IAP2 have been reported to possess antiapoptotic activity against a variety of stimuli in several… 
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