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BIRC2 protein, human

Known as: HIAP2, C-IAP1, Baculoviral IAP Repeat-Containing Protein 2 
Baculoviral IAP repeat-containing protein 2 (618 aa, ~70 kDa) is encoded by the human BIRC2 gene. This protein plays a role in the regulation of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Ubiquitin ligases are critical components of the ubiquitination process that determine substrate specificity and, in… Expand
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Highly Cited
2007
Highly Cited
2007
Inhibitor of apoptosis (IAP) proteins are antiapoptotic regulators that block cell death in response to diverse stimuli. They are… Expand
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Highly Cited
2005
Highly Cited
2005
Some members of the inhibitor of apoptosis (IAP) family suppress apoptosis by neutralizing caspases. The current model suggests… Expand
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Highly Cited
2003
Highly Cited
2003
Omi/HtrA2 is a mitochondrial serine protease that is released into the cytosol during apoptosis to antagonize inhibitors of… Expand
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Highly Cited
2003
Highly Cited
2003
NEMO (NF-kappaB essential modifier)/IKKgamma (IkappaB kinase-gamma) is required for the activation of the IkappaB kinase complex… Expand
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Highly Cited
2003
Highly Cited
2003
The inhibitor of apoptosis proteins (IAPs) plays a central role in repressing caspase-mediated cell death. However, little is… Expand
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Highly Cited
2001
Highly Cited
2001
The inhibitor of apoptosis protein (IAP) family consists of a number of evolutionarily conserved proteins that function to… Expand
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Highly Cited
1998
Highly Cited
1998
Tumor necrosis factor alpha (TNF-alpha) binding to the TNF receptor (TNFR) potentially initiates apoptosis and activates the… Expand
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Highly Cited
1996
Highly Cited
1996
The two cell surface receptors for tumor necrosis factor (TNF) interact with a number of intracellular signal transducing… Expand
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Highly Cited
1995
Highly Cited
1995
The 75 kDa tumor necrosis factor receptor (TNFR2) transduces extracellular signals via receptor-associated cytoplasmic proteins… Expand
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