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histone methyltransferase

Known as: histone H3 methyltransferase, histone methylase 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Histone-Lysine N-Methyltransferase
SUV39H2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Weaver Syndrome‐Associated EZH2 Protein Variants Show Impaired Histone Methyltransferase Function In Vitro
Weaver syndrome (WS) is a rare congenital disorder characterized by generalized overgrowth, macrocephaly, specific facial… 
Highly Cited
2012
Highly Cited
2012
Histone H3K9 methyltransferase G9a represses PPARγ expression and adipogenesis
PPARγ promotes adipogenesis while Wnt proteins inhibit adipogenesis. However, the mechanisms that control expression of these… 
Review
2011
Review
2011
Cancers and the NSD family of histone lysine methyltransferases.
Highly Cited
2011
Highly Cited
2011
Interplay between HDAC3 and WDR5 is essential for hypoxia-induced epithelial-mesenchymal transition.
Highly Cited
2009
Highly Cited
2009
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf–Hirschhorn syndrome
Diverse histone modifications are catalysed and recognized by various specific proteins, establishing unique modification… 
Highly Cited
2007
Highly Cited
2007
G9a Histone Methyltransferase Contributes to Imprinting in the Mouse Placenta
ABSTRACT Whereas DNA methylation is essential for genomic imprinting, the importance of histone methylation in the allelic… 
Highly Cited
2007
Highly Cited
2007
Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes
PRC2 is thought to be the histone methyltransferase (HMTase) responsible for H3‐K27 trimethylation at Polycomb target genes. Here… 
Highly Cited
2003
Highly Cited
2003
mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression.
Highly Cited
2003
Highly Cited
2003
Inactivation of a histone methyltransferase by mutations in human cancers.
Histone methyltransferase (HMT)(1) class enzymes that methylate lysine residues of histones or proteins contain a conserved… 
Highly Cited
2001
Highly Cited
2001
The Polycomb-Group GeneEzh2 Is Required for Early Mouse Development
ABSTRACT Polycomb-group (Pc-G) genes are required for the stable repression of the homeotic selector genes and other… 
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