grepafloxacin

Known as: (+--)-1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, 3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-, (RS)-1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline- 3-carboxylic acid 
 
National Institutes of Health

Papers overview

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Review
2006
Review
2006
In recent years, withdrawal of marketed drugs including sertindole, grepafloxacin, and terfenadine owing to prolongation of the… (More)
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2002
2002
The purpose of this study was to clarify the contribution of P-glycoprotein to the bioavailability and intestinal secretion of… (More)
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2002
2002
We investigated the contribution of multidrug resistance-associated protein 2 (MRP2) to the secretory transport of grepafloxacin… (More)
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Highly Cited
2000
Highly Cited
2000
In an open, randomized, six-period crossover study, the pharmacokinetics of ciprofloxacin, gatifloxacin, grepafloxacin… (More)
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2000
2000
Grepafloxacin (GPFX) is a synthetic new quinolone antimicrobial agent that possesses an extensive tissue distribution and… (More)
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2000
2000
Grepafloxacin and levofloxacin transport by Caco-2 cell monolayers was examined to characterize the intestinal behavior of these… (More)
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1997
1997
This analysis was designed to characterize the population pharmacokinetics and pharmacodynamics of oral grepafloxacin (OPC-17,116… (More)
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Review
1997
Review
1997
Preclinical investigations with grepafloxacin showed that its toxicological profile is similar to that of other fluoroquinolones… (More)
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Review
1997
Review
1997
Grepafloxacin is a fluoroquinolone antibiotic which is rapidly absorbed in healthy volunteers following oral dosing. It reaches… (More)
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1994
1994
Agar dilution was used to compare the in vitro activity of CP 99,219 with those of ciprofloxacin, grepafloxacin, metronidazole… (More)
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