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grepafloxacin

Known as: (+--)-1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, 3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-, (RS)-1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline- 3-carboxylic acid 
 
National Institutes of Health

Papers overview

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Review
2006
Review
2006
In recent years, withdrawal of marketed drugs including sertindole, grepafloxacin, and terfenadine owing to prolongation of the… Expand
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Review
2003
Review
2003
Since their discovery in the early 1960s, the quinolone group of antibacterials has generated considerable clinical and… Expand
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Highly Cited
2002
Highly Cited
2002
The purpose of this study was to clarify the contribution of P-glycoprotein to the bioavailability and intestinal secretion of… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT The mutant prevention concentration (MPC) represents a threshold above which the selective proliferation of resistant… Expand
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Highly Cited
2000
Highly Cited
2000
ABSTRACT In an open, randomized, six-period crossover study, the pharmacokinetics of ciprofloxacin, gatifloxacin, grepafloxacin… Expand
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Highly Cited
2000
Highly Cited
2000
Gatifloxacin, grepafloxacin, moxifloxacin and trovafloxacin are fluoroquinolones with enhanced Gram-positive activity while… Expand
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Highly Cited
2000
Highly Cited
2000
  • P. Ball
  • The Journal of antimicrobial chemotherapy
  • 2000
  • Corpus ID: 19018626
days 3‐5 of therapy have indicated a mean prolongation of QTc of 6 ms (� 26 ms) in 9.5% of moxifloxacin-treated patients compared… Expand
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1999
1999
Infections caused by non-tuberculous mycobacteria and multidrug-resistant Mycobacterium tuberculosis are difficult to treat. New… Expand
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Highly Cited
1997
Highly Cited
1997
This analysis was designed to characterize the population pharmacokinetics and pharmacodynamics of oral grepafloxacin (OPC-17,116… Expand
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Highly Cited
1994
Highly Cited
1994
Agar dilution was used to compare the in vitro activity of CP 99,219 with those of ciprofloxacin, grepafloxacin, metronidazole… Expand
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