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grepafloxacin

Known as: (+--)-1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, 3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-, (RS)-1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline- 3-carboxylic acid 
National Institutes of Health

Papers overview

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Review
2006
Review
2006
In recent years, withdrawal of marketed drugs including sertindole, grepafloxacin, and terfenadine owing to prolongation of the… 
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Review
2005
Review
2005
BACKGROUND/PURPOSE Infrequent toxicities associated with certain drugs and drug classes have recently gained much attention from… 
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Review
2003
Review
2003
Since their discovery in the early 1960s, the quinolone group of antibacterials has generated considerable clinical and… 
Review
2002
Review
2002
The new fluoroquinolones (clinafloxacin, gatifloxacin, gemifloxacin, grepafloxacin, levofloxacin, moxifloxacin, sitafloxacin… 
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Highly Cited
2001
Highly Cited
2001
ABSTRACT The mutant prevention concentration (MPC) represents a threshold above which the selective proliferation of resistant… 
Highly Cited
2001
Highly Cited
2001
Administration of certain fluoroquinolone antibacterials has been associated with prolongation of the QT interval on the… 
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Review
2000
Review
2000
  • P. Ball
  • The Journal of antimicrobial chemotherapy
  • 2000
  • Corpus ID: 2838418
The quinolones have evolved from antibacterial agents with a limited spectrum of predominantly anti-gram-negative antimicrobial… 
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Highly Cited
2000
Highly Cited
2000
ABSTRACT In an open, randomized, six-period crossover study, the pharmacokinetics of ciprofloxacin, gatifloxacin, grepafloxacin… 
Highly Cited
1997
Highly Cited
1997
This analysis was designed to characterize the population pharmacokinetics and pharmacodynamics of oral grepafloxacin (OPC-17,116… 
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Highly Cited
1994
Highly Cited
1994
Agar dilution was used to compare the in vitro activity of CP 99,219 with those of ciprofloxacin, grepafloxacin, metronidazole…