glutamate decarboxylase activity

Known as: gamma-glutamate decarboxylase activity, L-aspartate-alpha-decarboxylase activity, cysteic acid decarboxylase activity 
Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2. [EC:4.1.1.15]
National Institutes of Health

Related topics

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1 relation

Broader (1)

glutamate decarboxylation to succinate

Papers overview

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2009
2009
Glutamate Uptake Triggers Transporter-Mediated GABA Release from Astrocytes
BACKGROUND Glutamate (Glu) and gamma-aminobutyric acid (GABA) transporters play important roles in regulating neuronal activity… (More)
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2009
2009
An examination of aspartate decarboxylase and glutamate decarboxylase activity in mosquitoes
A major pathway of beta-alanine synthesis in insects is through the alpha-decarboxylation of aspartate, but the enzyme involved… (More)
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Highly Cited
2001
Highly Cited
2001
A glutamate decarboxylase system protects Listeria monocytogenes in gastric fluid.
We observed that glutamate greatly enhances the survival of Listeria monocytogenes in gastric fluid, a phenomenon that is… (More)
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Highly Cited
1997
Highly Cited
1997
Metabolism and functions of gamma-aminobutyric acid.
Gamma-aminobutyric acid (GABA), a four-carbon non-protein amino acid, is a significant component of the free amino acid pool in… (More)
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1994
1994
Decrease of glutamate decarboxylase activity after in vivo cortical infusion of gamma-aminobutyric acid.
gamma-Aminobutyric acid (GABA) levels and the activity of glutamate decarboxylase were measured in homogenates of rat brain… (More)
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1991
1991
Cofactor interactions and the regulation of glutamate decarboxylase activity
More than 50% of glutamate decarboxylase (GAD) in brain is present as apoenzyme. Recent work has opened the possibility that… (More)
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1982
1982
Plasma glutamate decarboxylase activity in neuropsychiatry
Plasma glutamate decarboxylase (GAD) activity was measured in patients with endogenous psychoses and neurologic diseases… (More)
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1977
1977
Glutamate decarboxylase (GAD) and γ-aminobutyric acid (GABA) in discrete nuclei of hypothalamus and substantia nigra
The distribution of L-glutamate decarboxylase activity (GAD) and gamma-aminobutyric acid (GABA) was investigated in the… (More)
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1977
1977
Origin of glutamate-decarboxylase (GAD)-containing cells in discrete hypothalamic nuclei
Glutamate decarboxylase activity (GAD) was assayed in discrete hypothalamic nuclei in the rat following lesions of the major… (More)
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Highly Cited
1976
Highly Cited
1976
High concentration of GABA and high glutamate decarboxylase activity in rat pancreatic islets and human insulinoma.
The concentration of gamma-aminobutyric acid (GABA) and the activity of glutamate decarboxylase (GAD) in rat and human pancreas… (More)
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