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glutamate decarboxylase activity

Known as: gamma-glutamate decarboxylase activity, L-aspartate-alpha-decarboxylase activity, cysteic acid decarboxylase activity 
Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2. [EC:4.1.1.15]
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

glutamate decarboxylation to succinate

Papers overview

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Highly Cited
1995
Highly Cited
1995
Chronicl-DOPA treatment differentially regulates gene expression of glutamate decarboxylase, preproenkephalin and preprotachykinin in the striatum of 6-hydroxydopamine-lesioned rat
1994
1994
Role of Protein Phosphorylation in Regulation of Brain L-Glutamate Decarboxylase Activity.
In the brain, the gamma-aminobutyric acid (GABA) level is primarily controlled by the activity of its synthesizing enzyme, L… 
1991
1991
Cofactor interactions and the regulation of glutamate decarboxylase activity
More than 50% of glutamate decarboxylase (GAD) in brain is present as apoenzyme. Recent work has opened the possibility that… 
1984
1984
The dissociation of evoked release of [3H]-GABA and of endogenous GABA from chick retina in vitro.
Highly Cited
1978
Highly Cited
1978
The effect of parenteral glutamate treatment on the localization of neurotransmitters in the mediobasal hypothalamus
1978
1978
A COMPARISON OF MICRODISTRIBUTIONS OF TAURINE AND CYSTEINE SULPHINATE DECARBOXYLASE ACTIVITY WITH THOSE OF GABA AND l‐GLUTAMATE DECARBOXYLASE ACTIVITY IN RAT SPINAL CORD AND THALAMUS
Abstract— Distribution profiles of taurine and activity of cysteine sulphinate decarboxylase (CSD), the enzyme catalysing the… 
Highly Cited
1977
Highly Cited
1977
Origin of glutamate-decarboxylase (GAD)-containing cells in discrete hypothalamic nuclei
1976
1976
The anticonvulsant activity of ketamine agains siezures induced by pentylenetetrazol and mercaptopropionic acid.
Highly Cited
1975
Highly Cited
1975
Evidence for a role of glutamate decarboxylase activity as a regulatory mechanism of cerebral excitability
AMPLE experimental evidence indicates that GABA is an inhibitory synaptic transmitter in the CNS of mammals. This evidence can be… 
Review
1953
Review
1953
Pyridoxin Deficiency in the Rat: Liver L-Cysteic Acid Decarboxylase Activity and Urinary Amino-acids
A recent survey of the urinary amino-acids of various animals (Datta & Harris, 1951, 1953) has shown taurine to be present in the… 
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