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glutamate decarboxylation to succinate

Known as: degradation of glutamate to succinate through GABA, glutamate degradation via 4-aminobutyrate, gamma-aminobutyrate shunt 
The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it… 
National Institutes of Health

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4-aminobutyrate aminotransferase activityglutamate decarboxylase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Elimination of KATP Channels in Mouse Islets Results in Elevated [U-13C]Glucose Metabolism, Glutaminolysis, and Pyruvate Cycling but a Decreased γ-Aminobutyric Acid Shunt*
Pancreatic beta cells are hyper-responsive to amino acids but have decreased glucose sensitivity after deletion of the… 
2006
2006
Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives.
Highly Cited
2003
Highly Cited
2003
Vigabatrin, but not Gabapentin or Topiramate, Produces Concentration‐related Effects on Enzymes and Intermediates of the GABA Shunt in Rat Brain and Retina
Summary:  Purpose: The antiepileptic drug (AED) vigabatrin (VGB), which exerts its pharmacologic effects on the γ‐aminobutyric… 
2003
2003
The altered expression of GABA shunt enzymes in the gerbil hippocampus before and after seizure generation
2001
2001
The alteration of γ-aminobutyric acid-transaminase expression in the gerbil hippocampus induced by seizure
2000
2000
Plant succinic semialdehyde dehydrogenase: dissection of nucleotide binding by surface plasmon resonance and fluorescence spectroscopy.
Recent kinetic studies revealed distinct modes of inhibition of mitochondrial Arabidopsis thaliana succinic semialdehyde… 
1993
1993
Isolation and characterization of recombinant mitochondrial 4-aminobutyrate aminotransferase.
1990
1990
Effect of maternal iron deficiency on GABA shunt pathway of developing rat brain.
Iron deficiency during pregnancy and lactation (35 mg iron/kg diet) produced a significant reduction in liver nonheme iron in… 
1986
1986
Effect of early iron deficiency in rat on the gamma-aminobutyric acid shunt in brain.
Early iron deficiency in rat does not affect the weight or the protein, DNA, and RNA content but results in a slight reduction in… 
1983
1983
Cortical GABA Turnover During Bicuculline Seizures in Rats
Abstract: The rate of cortical γ‐aminobutyric acid (GABA) turnover was estimated by determining the rate of GABA accumulation… 
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