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garenoxacin

Known as: 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Currently, a standard third-line therapy for Helicobacter pylori (H. pylori) eradication remains to be established. Quinolones… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT The pharmacodynamic properties governing the activities of antibiotics against intracellular Staphylococcus aureus are… Expand
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Highly Cited
2005
Highly Cited
2005
ABSTRACT Ciprofloxacin is subject to efflux from J774 macrophages through a multidrug resistance-related protein-like transporter… Expand
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Highly Cited
2005
Highly Cited
2005
The emergence of resistance to antibiotics is a serious problem often related to suboptimal drug dosing; such suboptimal dosing… Expand
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Highly Cited
2005
Highly Cited
2005
OBJECTIVES Quinolones accumulate in eukaryotic cells and show activity against a large array of intracellular organisms, but… Expand
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Long-term therapy for anthrax might induce antimicrobial resistance in Bacillus anthracis. The aim of the present study… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Limited data are available on Chryseobacterium spp. leading to an evaluation of the patient demographics and… Expand
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Review
2003
Review
2003
Since their discovery in the early 1960s, the quinolone group of antibacterials has generated considerable clinical and… Expand
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Highly Cited
2003
Highly Cited
2003
ABSTRACT The in vitro susceptibilities to garenoxacin (BMS-284756), an investigational des-fluoroquinolone, and eight other… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT We determined the target enzyme interactions of garenoxacin (BMS-284756, T-3811ME), a novel desfluoroquinolone, in… Expand
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