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Helicobacter pylori is now well known as an important pathogen related to the development of gastric cancer. However, some… Expand Currently, a standard third-line therapy for Helicobacter pylori (H. pylori) eradication remains to be established. Quinolones… Expand ABSTRACT The pharmacodynamic properties governing the activities of antibiotics against intracellular Staphylococcus aureus are… Expand ABSTRACT Ciprofloxacin is subject to efflux from J774 macrophages through a multidrug resistance-related protein-like transporter… Expand The emergence of resistance to antibiotics is a serious problem often related to suboptimal drug dosing; such suboptimal dosing… Expand OBJECTIVES
Quinolones accumulate in eukaryotic cells and show activity against a large array of intracellular organisms, but… Expand ABSTRACT Limited data are available on Chryseobacterium spp. leading to an evaluation of the patient demographics and… Expand Since their discovery in the early 1960s, the quinolone group of antibacterials has generated considerable clinical and… Expand ABSTRACT The in vitro susceptibilities to garenoxacin (BMS-284756), an investigational des-fluoroquinolone, and eight other… Expand ABSTRACT We determined the target enzyme interactions of garenoxacin (BMS-284756, T-3811ME), a novel desfluoroquinolone, in… Expand