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garenoxacin

Known as: 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Helicobacter pylori is now well known as an important pathogen related to the development of gastric cancer. However, some… Expand
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Highly Cited
2009
Highly Cited
2009
Currently, a standard third-line therapy for Helicobacter pylori (H. pylori) eradication remains to be established. Quinolones… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT The pharmacodynamic properties governing the activities of antibiotics against intracellular Staphylococcus aureus are… Expand
Highly Cited
2005
Highly Cited
2005
ABSTRACT Ciprofloxacin is subject to efflux from J774 macrophages through a multidrug resistance-related protein-like transporter… Expand
Highly Cited
2005
Highly Cited
2005
The emergence of resistance to antibiotics is a serious problem often related to suboptimal drug dosing; such suboptimal dosing… Expand
Highly Cited
2005
Highly Cited
2005
OBJECTIVES Quinolones accumulate in eukaryotic cells and show activity against a large array of intracellular organisms, but… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Limited data are available on Chryseobacterium spp. leading to an evaluation of the patient demographics and… Expand
Review
2003
Review
2003
Since their discovery in the early 1960s, the quinolone group of antibacterials has generated considerable clinical and… Expand
Highly Cited
2003
Highly Cited
2003
ABSTRACT The in vitro susceptibilities to garenoxacin (BMS-284756), an investigational des-fluoroquinolone, and eight other… Expand
Highly Cited
2002
Highly Cited
2002
ABSTRACT We determined the target enzyme interactions of garenoxacin (BMS-284756, T-3811ME), a novel desfluoroquinolone, in… Expand