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garenoxacin

Known as: 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
National Institutes of Health

Related topics

Related topics

8 relations

Broader (3)

Anti-Bacterial AgentsFluoroquinolonesTopoisomerase II Inhibitors

Narrower (1)

BMS 284756
Garenoxacin MesylateGarenoxacin:Susc:Pt:Isolate:OrdQnGarenoxacin:Susc:Pt:Isolate:OrdQn:Agar diffusionGarenoxacin:Susc:Pt:Isolate:OrdQn:MIC

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Quinolone-Based Third-Line Therapy for Helicobacter pylori Eradication
Currently, a standard third-line therapy for Helicobacter pylori (H. pylori) eradication remains to be established. Quinolones… 
Highly Cited
2006
Highly Cited
2006
Characterization of fluoroquinolone-resistant beta-hemolytic Streptococcus spp. isolated in North America and Europe including the first report of fluoroquinolone-resistant Streptococcus dysgalactiae…
Highly Cited
2006
Highly Cited
2006
Pharmacodynamic Evaluation of the Intracellular Activities of Antibiotics against Staphylococcus aureus in a Model of THP-1 Macrophages
ABSTRACT The pharmacodynamic properties governing the activities of antibiotics against intracellular Staphylococcus aureus are… 
Highly Cited
2006
Highly Cited
2006
Analysis of Salmonella spp. with resistance to extended-spectrum cephalosporins and fluoroquinolones isolated in North America and Latin America: report from the SENTRY Antimicrobial Surveillance…
Highly Cited
2005
Highly Cited
2005
Influence of Efflux Transporters on the Accumulation and Efflux of Four Quinolones (Ciprofloxacin, Levofloxacin, Garenoxacin, and Moxifloxacin) in J774 Macrophages
ABSTRACT Ciprofloxacin is subject to efflux from J774 macrophages through a multidrug resistance-related protein-like transporter… 
Highly Cited
2005
Highly Cited
2005
Bacterial-population responses to drug-selective pressure: examination of garenoxacin's effect on Pseudomonas aeruginosa.
The emergence of resistance to antibiotics is a serious problem often related to suboptimal drug dosing; such suboptimal dosing… 
2005
2005
Comparison of the Minimum Inhibitory, Mutant Prevention and Minimum Bactericidal Concentrations of Ciprofloxacin, Levofloxacin and Garenoxacin Against Enteric Gram-negative Urinary Tract Infection…
Abstract Acute, uncomplicated urinary tract infections (UTIs) are among the most commonly encountered bacterial infections and… 
Highly Cited
2005
Highly Cited
2005
Comparative activity of quinolones (ciprofloxacin, levofloxacin, moxifloxacin and garenoxacin) against extracellular and intracellular infection by Listeria monocytogenes and Staphylococcus aureus in…
OBJECTIVES Quinolones accumulate in eukaryotic cells and show activity against a large array of intracellular organisms, but… 
Highly Cited
2003
Highly Cited
2003
In Vitro Susceptibilities to and Bactericidal Activities of Garenoxacin (BMS-284756) and Other Antimicrobial Agents against Human Mycoplasmas and Ureaplasmas
ABSTRACT The in vitro susceptibilities to garenoxacin (BMS-284756), an investigational des-fluoroquinolone, and eight other… 
Highly Cited
2002
Highly Cited
2002
Dual Targeting of DNA Gyrase and Topoisomerase IV: Target Interactions of Garenoxacin (BMS-284756, T-3811ME), a New Desfluoroquinolone
ABSTRACT We determined the target enzyme interactions of garenoxacin (BMS-284756, T-3811ME), a novel desfluoroquinolone, in… 
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