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febrifugine

Known as: 3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropyl)- 4(3H)-quinazolinone 
 
National Institutes of Health

Papers overview

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2017
2017
ABSTRACT The KEAP1‐NRF2 system regulates the cellular defence against oxidative and xenobiotic stresses. NRF2 is a transcription… Expand
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2015
2015
The emergence of drug resistance is a major limitation of current antimalarials. The discovery of new druggable targets and… Expand
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Highly Cited
2013
Highly Cited
2013
Febrifugine is the active component of the Chinese herb Chang Shan (Dichroa febrifuga Lour.), which has been used for treating… Expand
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Highly Cited
2012
Highly Cited
2012
Febrifugine, the bioactive constituent of one of the 50 fundamental herbs of traditional Chinese medicine, has been characterized… Expand
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2010
2010
A series of 2-substituted and 2,3-substituted quinazolin -4(3H)-one derivatives were designed and synthesized based on the… Expand
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2009
2009
Febrifugine is an alkaloid isolated from Dichroa febrifuga Lour as the active component against Plasmodium falciparum. Adverse… Expand
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2006
2006
Febrifugine (1), a quinazoline alkaloid, isolated from Dichroa febrifuga roots, shows powerful antimalarial activity against… Expand
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2005
2005
Febrifugine is the active principal isolated 50 years ago from the Chinese herb chang shan (Dichroa febrifuga Lour), which has… Expand
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2002
2002
Although febrifugine (1) and isofebrifugine (2), alkaloids isolated from roots of the Dichroa febrifuga plant, show powerful… Expand
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1999
1999
Febrifugine (1) and isofebrifugine (2), isolated from the roots of Dichroa febrifuga Lour. (Chinese name: Cháng Shan), are active… Expand
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