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febrifugine

Known as: 3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropyl)- 4(3H)-quinazolinone 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

PiperidinesQuinazolines

Narrower (1)

isofebrifugine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
The role of halofuginone in fibrosis: more to be explored?
Fibrosis, which can be defined as an abnormal or excessive accumulation of extracellular matrix (ECM), particularly fibrillar… 
2007
2007
Seasonal variation in the content of a febrifugine and isofebrifugine alkaloid mixture in aerial parts of Hydrangea macrophylla var. Otaksa, with special reference to its antimalarial activity
Febrifugine and isofebrifugine alkaloid mixtures extracted from the leaves and buds of Hydrangea macrophylla var. Otaksa… 
2005
2005
Concise synthesis of dl-febrifugine.
Racemic compound (1) of the antimalarial agents febrifugine (d-1) was synthesized using an stereoselective Michael reaction of an… 
Review
2005
Review
2005
The Anti-Malarial Action of Changshan (Febrifugine): A Review
The plant qinghao (Artemesia annua) has provided the world with a valuable anti-malarial drug (qinghaosu). Another useful anti… 
2003
2003
Combination effects of chloroquine with the febrifugine and isofebrifugine mixture against a blood‐induced infection with chloroquine‐resistant Plasmodium berghei NK65 in ICR mice
The combination effects of chloroquine with a mixture of febrifugine and isofebrifugine were evaluated against a blood‐induced… 
2001
2001
Synthesis and antimalarial activity of febrifugine derivatives.
The regioisomers (2a,b) of the piperidine ring of febrifugine (1a) and isofebrifugine (1b) were synthesized from 4-allyl-3… 
1999
1999
Total Synthesis of dl-Febrifugine and dl-Isofebrifugine
Racemic compounds (1 and 2) of the antimalarial agents febrifugine (d-1) and isofebrilugine (d-2) were synthesized using an… 
Review
1984
Review
1984
The quinazoline alkaloids.
Quinazoline (1) is a building block for approximately eighty naturally occurring alkaloids isolated from a number of families of… 
1975
1975
Laboratory studies with some recent anticoccidials
The activities of monensin, lasalocid and halofuginone against Eimeria tenella, E. brunetti and E. necatrix have been studied… 
1970
1970
Febrifugine antimalarial agents. 1. Pyridine analogs of febrifugine.
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