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Visceral leishmaniasis affects people from 70 countries worldwide, mostly from Indian, African and south American continent. The… Expand The cytoplasmic prolyl-tRNA synthetase of Plasmodium falciparum is a dual-stage therapeutic target for drug development. An… Expand The trans-2,3-disubstituted piperidine, quinazolinone-containing natural product febrifugine (also known as dichroine B) and its… Expand Febrifugine, one of the fifty fundamental herbs of traditional Chinese medicine, has been characterized for its therapeutic… Expand Febrifugine (1), a quinazoline alkaloid, isolated from Dichroa febrifuga roots, shows powerful antimalarial activity against… Expand ABSTRACT Febrifugine is the active principal isolated 50 years ago from the Chinese herb chang shan (Dichroa febrifuga Lour… Expand Although febrifugine (1) and isofebrifugine (2), alkaloids isolated from roots of the Dichroa febrifuga plant, show powerful… Expand Reaction of (S)-2-(tert-butyldiphenylsilyloxy)-5-(mesyloxy)pentanal with hydroxylamine in allyl alcohol brought about… Expand Febrifugine (1) and isofebrifugine (2), isolated from the roots of Dichroa febrifuga Lour. (Chinese name: Cháng Shan), are active… Expand Antimalarial alkaloids febrifugine (1) and isofebrifugine (2) were efficiently synthesized from simple achiral starting materials… Expand