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febrifugine

Known as: 3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropyl)- 4(3H)-quinazolinone 
National Institutes of Health

Papers overview

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2017
2017
Visceral leishmaniasis affects people from 70 countries worldwide, mostly from Indian, African and south American continent. The… Expand
2015
2015
The cytoplasmic prolyl-tRNA synthetase of Plasmodium falciparum is a dual-stage therapeutic target for drug development. An… Expand
Review
2014
Review
2014
The trans-2,3-disubstituted piperidine, quinazolinone-containing natural product febrifugine (also known as dichroine B) and its… Expand
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Highly Cited
2012
Highly Cited
2012
Febrifugine, one of the fifty fundamental herbs of traditional Chinese medicine, has been characterized for its therapeutic… Expand
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Highly Cited
2006
Highly Cited
2006
Febrifugine (1), a quinazoline alkaloid, isolated from Dichroa febrifuga roots, shows powerful antimalarial activity against… Expand
Highly Cited
2005
Highly Cited
2005
ABSTRACT Febrifugine is the active principal isolated 50 years ago from the Chinese herb chang shan (Dichroa febrifuga Lour… Expand
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Highly Cited
2002
Highly Cited
2002
Although febrifugine (1) and isofebrifugine (2), alkaloids isolated from roots of the Dichroa febrifuga plant, show powerful… Expand
Highly Cited
2001
Highly Cited
2001
Reaction of (S)-2-(tert-butyldiphenylsilyloxy)-5-(mesyloxy)pentanal with hydroxylamine in allyl alcohol brought about… Expand
Highly Cited
1999
Highly Cited
1999
Febrifugine (1) and isofebrifugine (2), isolated from the roots of Dichroa febrifuga Lour. (Chinese name: Cháng Shan), are active… Expand
Highly Cited
1999
Highly Cited
1999
Antimalarial alkaloids febrifugine (1) and isofebrifugine (2) were efficiently synthesized from simple achiral starting materials… Expand