isofebrifugine

Febrifugine is an alkaloid with potent antimalarial activity isolated from Dichroa febrifuga and Hydrangea umbellate, and it… Expand

Cytokine and antibody production was investigated during the course of resolution of primary infection in Plasmodium yoelii 17XL… Expand

The combination effects of chloroquine with a mixture of febrifugine and isofebrifugine were evaluated against a blood-induced… Expand

The antimalarial activity of Hydrangea macrophylla var. Otaksa alkaloids was evaluated against Plasmodium yoelii 17XL, P. berghei… Expand

Quinazolinone type alkaloids, febrifugine (1) and isofebrifugine (2), isolated from Dichroa febrifuga roots, show powerful… Expand

The antimalarial activity of the fractions isolated from the leaves of Hydrangea macrophylla Seringe var. Otaksa Makino was… Expand

Two quinazolone alkaloids, (+)-febrifugine (1) and isofebrifugine (2), along with three coumarin derivatives, 6-hydroxy coumarin… Expand

Although febrifugine (1) and isofebrifugine (2), alkaloids isolated from roots of the Dichroa febrifuga plant, show powerful… Expand

Antimalarial alkaloids febrifugine (1) and isofebrifugine (2) were efficiently synthesized from simple achiral starting materials… Expand

Dichroa febrifuga has been employed by Chinese physicians as a medical cure for malaria since ancient times. Up to the present… Expand