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Antimalarial activity of methanolic extracts from plants used in Kenyan ethnomedicine and their interactions with chloroquine (CQ) against a CQ-tolerant rodent parasite, in mice.
Formation of antioxidants from (-)-epigallocatechin gallate in mild alkaline fluids, such as authentic intestinal juice and mouse plasma.
Phytoestrogens from Aspalathus linearis.
- N. Shimamura, T. Miyase, K. Umehara, T. Warashina, S. Fujii
- ChemistryBiological and Pharmaceutical Bulletin
- 1 June 2006
From the leaves of Aspalathus linearis, 24 known compounds and a new one, aspalalinin (25), were isolated. The structures of the compounds were determined mainly based on spectral evidence. The…
Simultaneous determination of twelve tea catechins by high-performance liquid chromatography with electrochemical detection.
A high-performance liquid chromatographic method with electrochemical detection was developed for the determination of twelve tea catechins, sensitive to and appropriate for the simultaneous determination of various biologically active catechin in green tea.
Chemical Studies on the Constituents of Polygonum nodosum
A new cyclobutane derivative, which may be formed from dehydrokawain by [2+2] cycloaddition, named compound B (8a), mp 226-227°C, C28H24O6, and a new flavanonol, named compound C (10a), mp 142-143°C,…
Studies on the constituents of leaves of Citrus unshiu Marcov.
glycosides 2-phenylethylƒÀ3-D-glucopyranoside(1)and 2-phenylethyl D-rutinoside(2),and the triterpenoids limonin(5)and friedelin(6)from the leaves of this plant. 2-Phenylethyl fl-D-glucopyranoside(1),…
Inhibitors of xanthine oxidase from the flowers and buds of Daphne genkwa.
- T. Noro, Y. Oda, T. Miyase, A. Ueno, S. Fukushima
- Chemistry, MedicineChemical & pharmaceutical bulletin
- 25 November 1983
Xanthine oxidase (XO) inhibitors were isolated from the flowers and buds of Daphne genkwa SIEB and were identified as genkwanin (1), apigenin (2), luteolin 7-methyl ether (3) and lutenolin (4).
Antiplasmodial triterpenoids from Ekebergia capensis.
Ten new triterpenoid compounds isolated from the stem bark of Ekebergia capensis were found to exhibit moderate antiplasmodial activity and were screened in vitro against both chloroquine (CQ)-sensitive and -resistant Plasmodium falciparum isolates.
Studies on absorption, distribution, excretion and metabolism of ginseng saponins. VII. Comparison of the decomposition modes of ginsenoside-Rb1 and -Rb2 in the digestive tract of rats.
- M. Karikura, T. Miyase, H. Tanizawa, T. Taniyama, Y. Takino
- ChemistryChemical and pharmaceutical bulletin
- 25 September 1991
It appears that hydrolysis by beta-glucosidase, which is present in the rat large intestine, is distinct from that by crude hesperidinase.
Green tea polyphenols: novel and potent inhibitors of squalene epoxidase.
It was demonstrated for the first time that the cholesterol lowering effect of green tea may be attributed to their potent SE inhibition activities, and that EGCG inhibited SE in noncompetitive, and non-time-dependent manner.