Skip to search formSkip to main contentSkip to account menu

fazarabine

Known as: 5 azacytosine arabinoside, Kymarabine, arabinosyl-5-azacytosine 
An orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action… 
National Institutes of Health

Related topics

Related topics

8 relations

Broader (4)

Antineoplastic AgentsAzacitidineCytarabineNucleoside Analogs
DNA Synthesis InhibitionDNA-Directed DNA Polymeraseanalogs & derivatives

Narrower (1)

NSC 281272

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Antitumor drug cross-resistance in vivo in a cisplatin-resistant murine P388 leukemia
SummarySince 1978, over 50 clinically useful antitumor drugs or new candidate antitumor agents have been evaluated in vivo… 
Review
2002
Review
2002
DNA methyltransferase inhibitors-state of the art.
BACKGROUND DNA methylation is the addition of a methyl group to the 5 position of cytosine. It is an epigenetic process with… 
1990
1990
Enhancement of the toxicity and DNA incorporation of arabinosyl-5-azacytosine and 1-beta-D-arabinofuranosylcytosine by cyclopentenyl cytosine.
We evaluated the interaction of a biochemically active concentration of cyclopentenyl cytosine (CPE-C), an investigational… 
Highly Cited
1987
Highly Cited
1987
Sequence-specific effects of ara-5-aza-CTP and ara-CTP on DNA synthesis by purified human DNA polymerases in vitro: visualization of chain elongation on a defined template.
1-beta-D-arabinofuranosyl-5-aza-cytosine (ara-5-aza-Cyd) is an analog of 1-beta-D-arabinofuranosylcytosine (ara-C), which… 
1986
1986
Arabinofuranosyl-5-azacytosine: antitumor and cytotoxic properties.
Arabinofuranosyl-5-azacytosine (ara-AC), a nucleoside combining the structural elements of 5-azacytidine and… 
1986
1986
Mechanism of action of 1-beta-D-arabinofuranosyl-5-azacytosine and its effects in L1210 mouse leukemia cells.
Ara-5AC depresses the growth of L1210 cells in vivo in a manner that is schedule-independent and at the dose levels which are… 
1985
1985
Metabolism of 1-beta-D-arabinofuranosyl-5-azacytosine and incorporation into DNA of human T-lymphoblastic cells (Molt-4).
1-beta-D-Arabinofuranosyl-5-azacytosine (ara-5-aza-Cyd) had potent cytotoxicity against human T-type lymphoblastic cells in… 
Review
1985
Review
1985
Azapyrimidine nucleosides: metabolism and inhibitory mechanisms.
1984
1984
1-beta-D-arabinosyl-5-azacytosine. Cytocidal activity and effects on the synthesis and methylation of DNA in human colon carcinoma cells.
The cytocidal activity of arabinosyl-5-azacytosine (araAC) and its effect on the synthesis and methylation of DNA in the human… 
1979
1979
Synthesis and antitumor activity of 5-azacytosine arabinoside.
5-Azacytosine arabinoside (ara-AC) can be considered a combination of structural elements derived from the antitumor nucleosides… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)