Skip to search formSkip to main contentSkip to account menu

Cytarabine

Known as: Cytosine-.beta.-arabinoside, Cytosine-beta-arabinoside, Arabinoside, Cytosine 
An antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the triphosphate form… 
National Institutes of Health

Related topics

Related topics

45 relations

Narrower (24)

2'-fluoro-5-methylarabino-furanosylcytosine5'-palmitoyl cytarabine5-methyl ara-CAra-C
COPAD protocolF-MACHOP RegimenLarson RegimenVAPAC protocol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1987
Highly Cited
1987
Prognostic factors in childhood acute myelogenous leukemia.
The prognostic significance of initial clinical and laboratory parameters was evaluated in 125 children with acute myelogenous… 
Highly Cited
1986
Highly Cited
1986
Formation of cytosine glycol and 5,6-dihydroxycytosine in deoxyribonucleic acid on treatment with osmium tetroxide.
OsO4 selectively forms thymine glycol lesions in DNA. In the past, OsO4-treated DNA has been used as a substrate in studies of… 
Highly Cited
1986
Highly Cited
1986
Histone mRNA degradation in vivo: the first detectable step occurs at or near the 3' terminus
The first detectable step in the degradation of human H4 histone mRNA occurs at the 3' terminus in a cell-free mRNA decay system… 
Highly Cited
1985
Highly Cited
1985
Novobiocin inhibition of DNA excision repair may occur through effects on mitochondrial structure and ATP metabolism, not on repair topoisomerases.
Novobiocin inhibits DNA topoisomerases. It also inhibits excision repair of DNA photodamage, blocking both repair synthesis and… 
Highly Cited
1984
Highly Cited
1984
High-dose cytosine arabinoside and m-AMSA is effective therapy in relapsed acute nonlymphocytic leukemia.
High-dose cytosine arabinoside ( HDARAC ) and 4'-(9 acridinylamino) methane sulfon -m-anisidine (m-AMSA) was administered as… 
Highly Cited
1983
Highly Cited
1983
Genetic, biochemical, and cross-resistance studies with mutants of Chinese hamster ovary cells resistant to the anticancer drugs, VM-26 and VP16-213.
The effects of the anticancer drugs 4′-demethylepipodophyllotoxin thenylidene β-d-glucoside and 4′-demethylepipodophyllotoxin… 
Highly Cited
1979
Highly Cited
1979
Rationale for development of platinum analogs.
There is a great need for clinical trial of new second-generation platinum coordination compounds that might demonstrate greater… 
Highly Cited
1975
Highly Cited
1975
The specificity of different classes of ethylating agents toward various sites of HeLa cell DNA in vitro and in vivo.
The sites and extent of ethyl products of neutral ethylation of HeLa cell DNA by [14-C]diethyl sulfate, [14-C]ethyl… 
Highly Cited
1974
Highly Cited
1974
Effect of Cycloheximide on RNA Metabolism Early in Productive Infection with Adenovirus 2
The presence of cycloheximide during the early phase of adenovirus 2 replication causes an increase in the virus-specific content… 
Highly Cited
1969
Highly Cited
1969
The locus of action of 1-beta-d-arabinofuranosylcytosine in the cell cycle.
Summary By taking advantage of the fact that 1-β-d-arabinofuranosylcytosine is metabolized slowly by asynchronous Don-C cells in…