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Cytarabine

Known as: Cytosine-.beta.-arabinoside, Cytosine-beta-arabinoside, Arabinoside, Cytosine 
An antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the triphosphate form… 
National Institutes of Health

Related topics

Related topics

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Narrower (24)

2'-fluoro-5-methylarabino-furanosylcytosine5'-palmitoyl cytarabine5-methyl ara-CAra-C
COPAD protocolF-MACHOP RegimenLarson RegimenVAPAC protocol

Papers overview

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Highly Cited
1985
Highly Cited
1985
Double labeling and in vitro versus in vivo incorporation of bromodeoxyuridine in patients with acute nonlymphocytic leukemia.
A monoclonal antibody against bromodeoxyuridine (BrdUrd) was produced, and a rapid slide technique (RPMB technique) was developed… 
Highly Cited
1983
Highly Cited
1983
Cyclobutane-type pyrimidine photodimer formation and excision in human skin fibroblasts after irradiation with 313-nm ultraviolet light.
The formation and excision of 313-nm light-induced cyclobutane-type pyrimidine photodimers were determined in confluent cultures… 
Highly Cited
1983
Highly Cited
1983
Acute cerebellar dysfunction with high‐dose ARA‐C therapy
The authors report a patient with clinical and morphologic evidence of acute cerebellar toxicity after receiving high‐dose… 
Highly Cited
1982
Highly Cited
1982
Mechanisms that uncouple growth and differentiation in myeloid leukemia cells: restoration of requirement for normal growth-inducing protein without restoring induction of differentiation-inducing…
There are different macrophage- and granulocyte-inducing (MGI) proteins. Normal myeloid precursors are induced to multiply by one… 
Highly Cited
1982
Highly Cited
1982
Pharmacokinetics of continuous intravenous and subcutaneous infusions of cytosine arabinoside.
The pharmacokinetics of continuous subcutaneous cytosine arabinoside (ara-C) infusions were compared with continuous intravenous… 
Highly Cited
1979
Highly Cited
1979
Effect of thymidine on the sensitivity of cultured mouse tumor cells to 1-beta-D-arabinofuranosylcytosine.
Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to… 
Highly Cited
1978
Highly Cited
1978
Metabolism and intracellular retention of 1-beta-D-arabinofuranosylcytosine as predictors of response of animal tumors.
Abstract The uptake, phosphorylation of 1-β-d-arabinofuranosylcytosine (ara-C), and the intracellular retention of ara-C… 
Highly Cited
1977
Highly Cited
1977
Deoxyribonucleic acid relationships among marine vibrios pathogenic to fish.
Polynucleotide sequence relationships among 19 strains of marine vibrios, 15 of which were pathogenic to fish, were assessed by… 
Highly Cited
1975
Highly Cited
1975
Metabolism and selective effects of 1-beta-D-arabinofuranosylcytosine in L1210 and Host tissues in vivo.
The selectivity of action of 1-beta-D-arabinofuranosylcytosine (ara-C) against leukemic cells was studied in vivo. Dynamic state… 
Highly Cited
1966
Highly Cited
1966
Cytogenetic and morphologie abnormalities in human bone marrow cells during cytosine arabinoside therapy.
The cytogenetic and morphologic abnormalities arising in the bone marrow following therapy with 1-β-D-arabinofuranosylcytosine…