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Cytarabine

Known as: Cytosine-.beta.-arabinoside, Cytosine-beta-arabinoside, Arabinoside, Cytosine 
An antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the triphosphate form… 
National Institutes of Health

Related topics

Related topics

45 relations

Narrower (24)

2'-fluoro-5-methylarabino-furanosylcytosine5'-palmitoyl cytarabine5-methyl ara-CAra-C
COPAD protocolF-MACHOP RegimenLarson RegimenVAPAC protocol

Papers overview

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Review
2011
Review
2011
Self-sorting phenomena in complex supramolecular systems.
Nature successfully manages under extremely adverse conditions to accomplish intricate functions responsible for the regulation… 
Highly Cited
2006
Highly Cited
2006
Chemoimmunotherapy with hyper‐CVAD plus rituximab for the treatment of adult Burkitt and Burkitt‐type lymphoma or acute lymphoblastic leukemia
Adult Burkitt‐type lymphoma (BL) and acute lymphoblastic leukemia (B‐ALL) are rare entities composing 1% to 5% of non‐Hodgkin… 
Highly Cited
1997
Highly Cited
1997
Interferon alfa-2b combined with cytarabine versus interferon alone in chronic myelogenous leukemia. French Chronic Myeloid Leukemia Study Group.
BACKGROUND Treatment with interferon prolongs survival in chronic myelogenous leukemia. We conducted a clinical trial to assess… 
Review
1993
Review
1993
The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human populations.
  • M. Fenech
  • Mutation research
  • 1993
  • Corpus ID: 25907436
Highly Cited
1993
Highly Cited
1993
Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.
High levels of extracellular K+ ensure proper development and prolong survival of cerebellar granule neurons in culture. We find… 
Review
1991
Review
1991
Cytarabine and neurologic toxicity.
Cytarabine is an effective drug in the treatment of certain hematologic malignancies and its common toxicities are… 
Highly Cited
1988
Highly Cited
1988
Evidence from Sertoli cell-depleted rats indicates that spermatid number in adults depends on numbers of Sertoli cells produced during perinatal development.
To probe the relationship between the size of the Sertoli cell population, established during perinatal development, and… 
Highly Cited
1981
Highly Cited
1981
Sequence specificity of methylation in higher plant DNA
Although plant DNA has a high content of 5-methylcytosine (5mC1) very little is known about the distribution of this modification… 
Highly Cited
1968
Highly Cited
1968
Arabinosyl cytosine: a useful agent in the treatment of acute leukemia in adults.
Arabinosyl cytosine (ara-C), a synthetic pyrimidine nucleoside related to the normal metabolites cytidine and deoxycytidine, has… 
Highly Cited
1968
Highly Cited
1968
Inhibition of Mammalian DNA Polymerase by the 5′-Triphosphate of 1-β-d-Arabinofuranosylcytosine and the 5′-Triphosphate of 9-β-d-Arabinofuranosyladenine
Summary The 5′-triphosphate of 1-β-d-arabinofuranosylcytosine (ara-CTP) was tested as a substrate or inhibitor of polynucleotide… 
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