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Cytarabine

Known as: Cytosine-.beta.-arabinoside, Cytosine-beta-arabinoside, Arabinoside, Cytosine 
An antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the triphosphate form… 
National Institutes of Health

Related topics

Related topics

45 relations

Narrower (24)

2'-fluoro-5-methylarabino-furanosylcytosine5'-palmitoyl cytarabine5-methyl ara-CAra-C
COPAD protocolF-MACHOP RegimenLarson RegimenVAPAC protocol

Papers overview

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Highly Cited
1987
Highly Cited
1987
Prognostic factors in childhood acute myelogenous leukemia.
The prognostic significance of initial clinical and laboratory parameters was evaluated in 125 children with acute myelogenous… 
Highly Cited
1987
Highly Cited
1987
In vitro and in vivo effects of deferoxamine in neonatal acute leukemia
A six week old infant with acute leukemia failed to attain remission with chemotherapy. Because we previously demonstrated that… 
Highly Cited
1986
Highly Cited
1986
Formation of cytosine glycol and 5,6-dihydroxycytosine in deoxyribonucleic acid on treatment with osmium tetroxide.
OsO4 selectively forms thymine glycol lesions in DNA. In the past, OsO4-treated DNA has been used as a substrate in studies of… 
Highly Cited
1985
Highly Cited
1985
Novobiocin inhibition of DNA excision repair may occur through effects on mitochondrial structure and ATP metabolism, not on repair topoisomerases.
Novobiocin inhibits DNA topoisomerases. It also inhibits excision repair of DNA photodamage, blocking both repair synthesis and… 
Highly Cited
1984
Highly Cited
1984
High-dose cytosine arabinoside and m-AMSA is effective therapy in relapsed acute nonlymphocytic leukemia.
High-dose cytosine arabinoside ( HDARAC ) and 4'-(9 acridinylamino) methane sulfon -m-anisidine (m-AMSA) was administered as… 
Highly Cited
1979
Highly Cited
1979
Rationale for development of platinum analogs.
There is a great need for clinical trial of new second-generation platinum coordination compounds that might demonstrate greater… 
Highly Cited
1975
Highly Cited
1975
The specificity of different classes of ethylating agents toward various sites of HeLa cell DNA in vitro and in vivo.
The sites and extent of ethyl products of neutral ethylation of HeLa cell DNA by [14-C]diethyl sulfate, [14-C]ethyl… 
Highly Cited
1969
Highly Cited
1969
The locus of action of 1-beta-d-arabinofuranosylcytosine in the cell cycle.
Summary By taking advantage of the fact that 1-β-d-arabinofuranosylcytosine is metabolized slowly by asynchronous Don-C cells in… 
Highly Cited
1967
Highly Cited
1967
Transport and Phosphorylation as Factors in the Antitumor Action of Cytosine Arabinoside
Survival of mice bearing different transplantable leukemias and treated with cytosine arabinoside was compared with uptake and… 
Highly Cited
1966
Highly Cited
1966
Chloroplast DNA from Tobacco Leaves
DNA from tobacco leaf chloroplasts was isolated as a single component with a buoyant density in CsCl of 1.702 compared to 1.697… 
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