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Cytarabine

Known as: Cytosine-.beta.-arabinoside, Cytosine-beta-arabinoside, Arabinoside, Cytosine 
An antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the triphosphate form… 
National Institutes of Health

Related topics

Related topics

45 relations

Narrower (24)

2'-fluoro-5-methylarabino-furanosylcytosine5'-palmitoyl cytarabine5-methyl ara-CAra-C
COPAD protocolF-MACHOP RegimenLarson RegimenVAPAC protocol

Papers overview

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Highly Cited
1999
Highly Cited
1999
Common resistance mechanisms to deoxynucleoside analogues in variants of the human erythroleukaemic line K562
Resistant variants of the human leukaemic line K562 were developed using selection with the deoxynucleoside analogues cytosine… 
Highly Cited
1988
Highly Cited
1988
Modulation of arabinosylnucleoside metabolism by arabinosylnucleotides in human leukemia cells.
Previous studies have indicated that deoxycytidine kinase (dCK) is requisite and rate limiting in the phosphorylation of 1-beta-D… 
Highly Cited
1985
Highly Cited
1985
Progressive multifocal leukoencephalopathy: Clinical and radiographic features
Between April 1982 and March 1984 7 pathologically confirmed cases of progressive multifocal leukoencephalopathy (PML) were… 
Highly Cited
1985
Highly Cited
1985
High-dose cytosine arabinoside therapy with and without anthracycline antibiotics for remission reinduction of acute nonlymphoblastic leukemia.
Seventy-eight patients with acute nonlymphoblastic leukemia in relapse were treated with high-dose cytosine arabinoside (3 g/m2… 
Highly Cited
1985
Highly Cited
1985
Somatomedin-C synergizes with follicle-stimulating hormone in the acquisition of progestin biosynthetic capacity by cultured rat granulosa cells.
We have recently shown that nanomolar concentrations of somatomedin-C (Sm-C), are capable of enhancing the FSH-mediated (but not… 
Review
1976
Review
1976
Bisulfite modification of nucleic acids and their constituents.
Highly Cited
1974
Highly Cited
1974
The experimental antitumour properties of three congeners of the acridylmethanesulphonanilide (AMSA) series.
Highly Cited
1971
Highly Cited
1971
Effects of hydroxyurea and 1-beta-D-arabinofuranosyl-cytosine on deoxyribonucleotide pools in mouse embryo cells.
Mouse embryo cells incubated in medium with 0.5% serum contain only few cells which synthesize DNA. When the serum concentration… 
Highly Cited
1968
Highly Cited
1968
The incorporation of 3H-cytosine arabinoside and its effect on murine leukemic cells (L5178Y).
Review
1966
Review
1966
Introduction to the biochemistry of D-arabinosyl nucleosides.
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