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Cytarabine

Known as: Cytosine-.beta.-arabinoside, Cytosine-beta-arabinoside, Arabinoside, Cytosine 
An antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the triphosphate form… 
National Institutes of Health

Related topics

Related topics

45 relations

Narrower (24)

2'-fluoro-5-methylarabino-furanosylcytosine5'-palmitoyl cytarabine5-methyl ara-CAra-C
COPAD protocolF-MACHOP RegimenLarson RegimenVAPAC protocol

Papers overview

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Highly Cited
1986
Highly Cited
1986
Histone mRNA degradation in vivo: the first detectable step occurs at or near the 3' terminus
The first detectable step in the degradation of human H4 histone mRNA occurs at the 3' terminus in a cell-free mRNA decay system… 
Highly Cited
1985
Highly Cited
1985
Double labeling and in vitro versus in vivo incorporation of bromodeoxyuridine in patients with acute nonlymphocytic leukemia.
A monoclonal antibody against bromodeoxyuridine (BrdUrd) was produced, and a rapid slide technique (RPMB technique) was developed… 
Highly Cited
1982
Highly Cited
1982
Mechanisms that uncouple growth and differentiation in myeloid leukemia cells: restoration of requirement for normal growth-inducing protein without restoring induction of differentiation-inducing…
There are different macrophage- and granulocyte-inducing (MGI) proteins. Normal myeloid precursors are induced to multiply by one… 
Highly Cited
1982
Highly Cited
1982
Pharmacokinetics of continuous intravenous and subcutaneous infusions of cytosine arabinoside.
The pharmacokinetics of continuous subcutaneous cytosine arabinoside (ara-C) infusions were compared with continuous intravenous… 
Highly Cited
1979
Highly Cited
1979
Effect of thymidine on the sensitivity of cultured mouse tumor cells to 1-beta-D-arabinofuranosylcytosine.
Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to… 
Highly Cited
1978
Highly Cited
1978
Metabolism and intracellular retention of 1-beta-D-arabinofuranosylcytosine as predictors of response of animal tumors.
Abstract The uptake, phosphorylation of 1-β-d-arabinofuranosylcytosine (ara-C), and the intracellular retention of ara-C… 
Highly Cited
1975
Highly Cited
1975
Metabolism and selective effects of 1-beta-D-arabinofuranosylcytosine in L1210 and Host tissues in vivo.
The selectivity of action of 1-beta-D-arabinofuranosylcytosine (ara-C) against leukemic cells was studied in vivo. Dynamic state… 
Highly Cited
1974
Highly Cited
1974
Effect of Cycloheximide on RNA Metabolism Early in Productive Infection with Adenovirus 2
The presence of cycloheximide during the early phase of adenovirus 2 replication causes an increase in the virus-specific content… 
Highly Cited
1972
Highly Cited
1972
Integration of Simian Virus 40 Deoxyribonucleic Acid into the Deoxyribonucleic Acid of Permissive Monkey Kidney Cells
Integration of simian virus 40 (SV40) deoxyribonucleic acid (DNA) into cellular DNA occurred when permissive African green monkey… 
Highly Cited
1971
Highly Cited
1971
Studies on Nondefective Adenovirus-Simian Virus 40 Hybrid Viruses I. A Newly Characterized Simian Virus 40 Antigen Induced by the Ad2+ND1 Virus
The nondefective adenovirus 2 (Ad2)-simian virus 40 (SV40) hybrid virus, Ad2+ND1, does not induce heat-labile SV40 T antigen but…