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Cytarabine
Known as:
Cytosine-.beta.-arabinoside
, Cytosine-beta-arabinoside
, Arabinoside, Cytosine
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An antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the triphosphate form…
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National Institutes of Health
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Related topics
Related topics
45 relations
Narrower (24)
2'-fluoro-5-methylarabino-furanosylcytosine
5'-palmitoyl cytarabine
5-methyl ara-C
Ara-C
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COPAD protocol
F-MACHOP Regimen
Larson Regimen
VAPAC protocol
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
CPX-351 (cytarabine and daunorubicin) Liposome for Injection Versus Conventional Cytarabine Plus Daunorubicin in Older Patients With Newly Diagnosed Secondary Acute Myeloid Leukemia
J. Lancet
,
G. Uy
,
+18 authors
B. Medeiros
Journal of Clinical Oncology
2018
Corpus ID: 51703570
Purpose CPX-351 is a dual-drug liposomal encapsulation of cytarabine and daunorubicin that delivers a synergistic 5:1 drug ratio…
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Highly Cited
2009
Highly Cited
2009
Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study.
P. Fenaux
,
G. Mufti
,
+16 authors
L. Silverman
The Lancet Oncology
2009
Corpus ID: 33166964
Highly Cited
2003
Highly Cited
2003
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia.
S. O’Brien
,
F. Guilhot
,
+22 authors
B. Druker
New England Journal of Medicine
2003
Corpus ID: 20464466
BACKGROUND Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high response rates in patients with chronic…
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Highly Cited
2003
Highly Cited
2003
Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia.
T. Hughes
,
J. Kaeda
,
+8 authors
J. Radich
New England Journal of Medicine
2003
Corpus ID: 20591895
BACKGROUND In a randomized trial, 1106 patients with chronic myeloid leukemia (CML) in chronic phase were assigned to imatinib or…
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Highly Cited
1998
Highly Cited
1998
Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype.
C. Bloomfield
,
David S. Lawrence
,
+9 authors
R. J. Mayer
Cancer Research
1998
Corpus ID: 1570264
Advances in the treatment of acute myeloid leukemia (AML) have occurred with the introduction of new therapies including high…
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Highly Cited
1993
Highly Cited
1993
Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.
S. Kaufmann
,
S. Desnoyers
,
Y. Ottaviano
,
N. Davidson
,
G. Poirier
Cancer Research
1993
Corpus ID: 2339073
Apoptosis is a morphologically and biochemically distinct form of cell death that occurs under a variety of physiological and…
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Highly Cited
1991
Highly Cited
1991
Participation of p53 protein in the cellular response to DNA damage.
M. Kastan
,
O. Onyekwere
,
D. Sidransky
,
B. Vogelstein
,
R. Craig
Cancer Research
1991
Corpus ID: 11995070
The inhibition of replicative DNA synthesis that follows DNA damage may be critical for avoiding genetic lesions that could…
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Highly Cited
1980
Highly Cited
1980
Cellular differentiation, cytidine analogs and DNA methylation
Peter A. Jones
,
Shirley M. Taylor
Cell
1980
Corpus ID: 12649615
Review
1980
Review
1980
Comparative properties and methods of preparation of lipid vesicles (liposomes).
F. Szoka
,
D. Papahadjopoulos
Annual Review of Biophysics and Bioengineering
1980
Corpus ID: 31951375
IAbbreviations used in this article are as follows: AraC= l -,B-d arabinofuranosyl cytosine, Chol=cholesterol, DNA…
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Highly Cited
1974
Highly Cited
1974
Regulation of Herpesvirus Macromolecular Synthesis I. Cascade Regulation of the Synthesis of Three Groups of Viral Proteins
R. Honess
,
B. Roizman
Journal of Virology
1974
Corpus ID: 34186855
Based on evidence that 50% of herpes simplex 1 DNA is transcribed in HEp-2 cells in the absence of protein synthesis we examined…
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