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Cytarabine

Known as: Cytosine-.beta.-arabinoside, Cytosine-beta-arabinoside, Arabinoside, Cytosine 
An antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the triphosphate form… 
National Institutes of Health

Related topics

Related topics

45 relations

Narrower (24)

2'-fluoro-5-methylarabino-furanosylcytosine5'-palmitoyl cytarabine5-methyl ara-CAra-C
COPAD protocolF-MACHOP RegimenLarson RegimenVAPAC protocol

Papers overview

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Highly Cited
1999
Highly Cited
1999
Common resistance mechanisms to deoxynucleoside analogues in variants of the human erythroleukaemic line K562
Resistant variants of the human leukaemic line K562 were developed using selection with the deoxynucleoside analogues cytosine… 
Highly Cited
1991
Highly Cited
1991
Radioiodinated 1-(5-iodo-5-deoxy-beta-D-arabinofuranosyl)-2-nitroimidazole (iodoazomycin arabinoside: IAZA): a novel marker of tissue hypoxia.
1-(5-Iodo-5-deoxy-beta-D-arabinofuranosyl)-2-nitroimidazole (IAZA) has been synthesised and labeled with 125I. Radioiodinated… 
Highly Cited
1985
Highly Cited
1985
Somatomedin-C synergizes with follicle-stimulating hormone in the acquisition of progestin biosynthetic capacity by cultured rat granulosa cells.
We have recently shown that nanomolar concentrations of somatomedin-C (Sm-C), are capable of enhancing the FSH-mediated (but not… 
Highly Cited
1984
Highly Cited
1984
High-dose cytosine arabinoside and m-AMSA is effective therapy in relapsed acute nonlymphocytic leukemia.
High-dose cytosine arabinoside ( HDARAC ) and 4'-(9 acridinylamino) methane sulfon -m-anisidine (m-AMSA) was administered as… 
Highly Cited
1977
Highly Cited
1977
Regulation of Early and Late Simian Virus 40 Transcription: Overproduction of Early Viral RNA in the Absence of a Functional T-Antigen
Virus-specific RNA synthesized in monkey cells after infection by both wild-type simian virus 40 (SV40) and the early SV40… 
Highly Cited
1975
Highly Cited
1975
The specificity of different classes of ethylating agents toward various sites of HeLa cell DNA in vitro and in vivo.
The sites and extent of ethyl products of neutral ethylation of HeLa cell DNA by [14-C]diethyl sulfate, [14-C]ethyl… 
Highly Cited
1971
Highly Cited
1971
Effects of hydroxyurea and 1-beta-D-arabinofuranosyl-cytosine on deoxyribonucleotide pools in mouse embryo cells.
Mouse embryo cells incubated in medium with 0.5% serum contain only few cells which synthesize DNA. When the serum concentration… 
Highly Cited
1967
Highly Cited
1967
Transport and Phosphorylation as Factors in the Antitumor Action of Cytosine Arabinoside
Survival of mice bearing different transplantable leukemias and treated with cytosine arabinoside was compared with uptake and… 
Highly Cited
1967
Highly Cited
1967
Correlation between cell enlargement and nucleic acid and protein content of hela cells in unbalanced growth produced by inhibitors of DNA synthesis
HeLa cells in monolayer cultures were treated with the following inhibitors of DNA synthesis: mitomycin C, nitrogen mustard… 
Review
1966
Review
1966
Introduction to the biochemistry of D-arabinosyl nucleosides.
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