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fasudil

Known as: 1-(5-Isoquinolinesulfonyl)homopiperazine, 1H-1,4-Diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)-, Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine 
National Institutes of Health

Related topics

Related topics

9 relations

Narrower (4)

AT 877HA 1077fasudil hydrochloridefasudil mesylate

Broader (4)

Calcium Channel BlockersIsoquinolinesProtein Kinase InhibitorsVasodilator Agents
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Critical role of EphA4 in early brain injury after subarachnoid hemorrhage in rat
2015
2015
Acute effects of Rho-kinase inhibitor fasudil on pulmonary arterial hypertension in patients with congenital heart defects.
BACKGROUND We investigated the acute vasodilator effects of i.v. fasudil, a specific Rho-kinase inhibitor, on pulmonary… 
2013
2013
Intravitreal fasudil combined with bevacizumab for persistent diabetic macular edema: a novel treatment.
D espite recent advances in pharmacotherapy for diabeticmacular edema (DME), satisfyinganatomical and visual results are not… 
2008
2008
Analysis of pulmonary vasodilator responses to the Rho-kinase inhibitor fasudil in the anesthetized rat.
The small GTP-binding protein Rho and its downstream effector, Rho-kinase, are important regulators of vasoconstrictor tone. Rho… 
2007
2007
Anti-ischemic Effects of Fasudil, a Specific Rho-Kinase Inhibitor, in Patients With Stable Effort Angina
Epicardial coronary stenosis causes myocardial ischemia; however, the role of coronary microvessels is poorly understood in the… 
Highly Cited
2007
Highly Cited
2007
Fasudil Attenuates Myocardial Fibrosis in Association With Inhibition of Monocyte/Macrophage Infiltration in the Heart of DOCA/Salt Hypertensive Rats
Objective: To determine the effects of fasudil, a Rho-kinase inhibitor, on mineralocorticoid-induced myocardial remodeling, we… 
2001
2001
Involvement of Rho-kinase in vascular remodeling caused by long-term inhibition of nitric oxide synthesis in rats.
2001
2001
Antiischemic properties of fasudil in experimental models of vasospastic angina.
We studied the antiischemic properties of fasudil, a Rho-kinase inhibitor, in conscious rabbits with coronary vasospasm induced… 
2000
2000
Hemorheological abnormalities in experimental cerebral ischemia and effects of protein kinase inhibitor on blood fluidity.
2000
2000
The protein kinase inhibitor fasudil protects against ischemic myocardial injury induced by endothelin-1 in the rabbit.
Endothelin-1 (ET-1) induces severe pathologic conditions such as coronary spasm followed by vasospastic angina pectoris and acute… 
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