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fasudil

Known as: 1-(5-Isoquinolinesulfonyl)homopiperazine, 1H-1,4-Diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)-, Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine 
National Institutes of Health

Related topics

Related topics

9 relations

Narrower (4)

AT 877HA 1077fasudil hydrochloridefasudil mesylate

Broader (4)

Calcium Channel BlockersIsoquinolinesProtein Kinase InhibitorsVasodilator Agents
analogs & derivatives

Papers overview

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2015
2015
Impacts of Rho kinase inhibitor Fasudil on Rho/ROCK signaling pathway in rabbits with optic nerve injury.
OBJECTIVE The aim of this study was to study the impacts of Rho kinase inhibitor Fasudil on expressions of Rho/ROCK signaling… 
2010
2010
EFFECTS OF FASUDIL ON EXPRESSIONS OF Bcl-2,Bax AND HEMODYNAMICS IN INFARCTED MYOCARDIUM OF RATS
Objective To investigate the effects of fasudil on the expressions of Bcl-2,Bax and the hemodynamics in myocardium of rats with… 
2009
2009
Importance of Rac 1 Signaling Pathway Inhibition in the Pleiotropic Effects of HMG-CoA Reductase Inhibitors
MG-CoA reductase inhibitors (statins) are potent cholesterol-lowering drugs widely used in clinical practice for primary and… 
2009
2009
Study on the Pharmacokinetics of Fasudil, a selective Rho kinase inhibitor
Aim To study the pharmacokinetics of Fasudil. Design and Method The HPLC methods with UV detection were used for measurement of… 
2008
2008
Effect of fasudil on hemorheology in patients with acute ischemic stroke
Objective To observe the effects of fasudil on hemorheology in patients with acute ischemic stroke.Methods Eighty-five patients… 
2008
2008
Fasudil (a rho-kinase inhibitor) may specifically increase rCBF in spastic area
Pathophysiological mechanisms underlying vasospasm are diverse and not yet fully elucidated. However, it has recently been shown… 
2007
2007
Medico-economic evaluation for the treatment of acute ischemic stroke using a placebo-controlled clinical trial of fasudil
各種脳血管障害治療の医療経済分析は本邦では十分なされていない. 今回我々は脳梗塞急性期治療薬として効果が示された塩酸ファスジル (以下ファスジル) を, 70… 
2005
2005
Fasudil , a Rho -
Jih-Lie Tseng, Gary D. Deng, Sabine Schirm, Anthony Johns, Katalin Kauser, William P. Dole Feng, Meredith Halks-Miller, Mithra… 
2002
2002
The effects of a new vasodilator fasudil on delayed cerebral vasospasm after subarachnoid hemorrhage
Objective:To investigate the effects of a new agent fasudil on delayed cerebral vasospasm after subarachniod hemorrhage Methods… 
1998
1998
A Protein Kinase Inhibitor, Fasudil (AT‐877): A Novel Approach to Signal Transduction Therapy