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fasudil hydrochloride

National Institutes of Health

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fasudil

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2018
2018
RhoA/ROCK Signaling Pathway Mediates Shuanghuanglian Injection-Induced Pseudo-allergic Reactions
Background: Shuanghuanglian injection (SHLI) is a famous Chinese medicine used as an intravenous preparation for the treatment of… 
2015
2015
Effectiveness of intraarterial administration of fasudil hydrochloride for preventing symptomatic vasospasm after subarachnoid hemorrhage.
OBJECTIVE We examined the effect of intraarterial administration of fasudil hydrochloride (IAFC), a Rho kinase inhibitor, for the… 
2014
2014
The protective effect of fasudil pretreatment combined with ischemia postconditioning on myocardial ischemia/reperfusion injury in rats.
OBJECTIVE Ischemic postconditioning (IPO) and pharmacological pretreatment may reduce myocardial necrosis and apoptosis during… 
2013
2013
Intravitreal fasudil combined with bevacizumab for persistent diabetic macular edema: a novel treatment.
D espite recent advances in pharmacotherapy for diabeticmacular edema (DME), satisfyinganatomical and visual results are not… 
2013
2013
Protective effects of fasudil hydrochloride post-conditioning on acute myocardial ischemia/reperfusion injury in rats.
BACKGROUND In recent years, the alleviation of acute myocardial ischemia and reperfusion injury (MI/RI) during myocardial… 
2010
2010
Fasudil hydrochloride induces osteoblastic differentiation of stromal cell lines, C3H10T1/2 and ST2, via bone morphogenetic protein-2 expression.
Rho-kinase (ROK), downstream of the mevalonate pathway, is detrimental to vessels, and suppressing its activity is a target for… 
2007
2007
The Rho-Associated Kinase Inhibitor Fasudil Hydrochloride Enhances Neural Regeneration after Axotomy in the Peripheral Nervous System
Background: The Rho family of small GTPases is responsible for various processes involving actin cytoskeleton in eukaryotic cells… 
2005
2005
Activation of Rho-associated kinase during augmented contraction of the basilar artery to serotonin after subarachnoid hemorrhage.
Delayed cerebral vasospasm after subarachnoid hemorrhage (SAH) may be due, in part, to altered regulation of arterial smooth… 
1997
1997
Fasudil (HA1077), an intracellular calcium antagonist, improves neurological deficits and tissue potassium loss in focal cerebral ischemia in gerbils.
The effects of an intracellular calcium antagonist fasudil (HA 1077) on protein synthesis, ion derangement, brain edema, and the… 
1993
1993
Effects of Fasudil Hydrochloride on Cerebral Blood Flow in Patients with Chronic Cerebral Infarction
Summary: To evaluate the effect of the novel intracellular calcium antagonist fasudil hydrochloride, cerebral blood flow (CBF… 
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