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HA 1077
Known as:
HA-1077
, HA1077
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Isoquinolines
fasudil
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
The Effect of the Rho-Associated Protein Kinase Inhibitor, HA-1077, in the Rabbit Ocular Hypertension Model Induced by Water Loading
T. Fukunaga
,
K. Ikesugi
,
+4 authors
Y. Uji
Current Eye Research
2009
Corpus ID: 27615544
Purpose: The aim of this study was to investigate the intraocular pressure (IOP)-lowering effect of a new anti-glaucoma drug, the…
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2007
2007
Effects of HA-1077 and Y-27632, two rho-kinase inhibitors, in the human umbilical artery
M. Ark
,
Elif Özveren
,
+5 authors
E. Songu‐Mize
Cell Biochemistry and Biophysics
2007
Corpus ID: 185642
A role for the small G protein rho and rho-kinase has been shown in smooth muscle contraction regarding Ca++ sensitivity. However…
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2003
2003
Hyperosmotic-induced Protein Kinase N 1 Activation in a Vesicular Compartment Is Dependent upon Rac1 and 3-Phosphoinositide-dependent Kinase 1*
N. Torbett
,
A. Casamassima
,
P. Parker
Journal of Biological Chemistry
2003
Corpus ID: 32959630
Protein kinase N 1 (PKN1), which in part resembles yeast protein kinase C, has been shown to be under the control of Rho GTPases…
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Highly Cited
2001
Highly Cited
2001
Effects of protein kinase inhibitor, HA1077, on intraocular pressure and outflow facility in rabbit eyes.
Megumi Honjo
,
M. Inatani
,
+4 authors
H. Tanihara
A M A Archives of Ophthalmology
2001
Corpus ID: 39506515
OBJECTIVE To elucidate the roles of protein kinase in regulating the intraocular pressure (IOP) and outflow facility in rabbit…
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2001
2001
Rho-associated kinase phosphorylates MARCKS in human neuronal cells.
H. Nagumo
,
M. Ikenoya
,
+4 authors
Y. Sasaki
Biochemical and Biophysical Research…
2001
Corpus ID: 22916511
Myristoylated alanine-rich C kinase substrate (MARCKS) is a filamentous actin bundling protein and has multiple sites for…
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Review
2001
Review
2001
Effect of Fasudil HCl, a protein kinase inhibitor, on cerebral vasospasm.
M. Shibuya
,
T. Asano
,
Y. Sasaki
Acta neurochirurgica. Supplement
2001
Corpus ID: 930612
Fasudil HCl (HA1077, AT877, Eril) was first introduced as a unique vasodilator and intracellular calcium antagonist. It dilated…
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Highly Cited
2000
Highly Cited
2000
Protein kinase inhibition by fasudil hydrochloride promotes neurological recovery after spinal cord injury in rats.
Masahito Hara
,
Masakazu Takayasu
,
+4 authors
J. Yoshida
Journal of Neurosurgery
2000
Corpus ID: 13192607
OBJECT In Japan fasudil hydrochloride (HA1077), a protein kinase inhibitor, is widely administered to prevent vasospasm in…
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1995
1995
Selective inhibition of myosin phosphorylation and tension of hyperplastic arteries by the kinase inhibitor HA1077.
M. Seto
,
K. Shindo
,
K. Ito
,
Y. Sasaki
European Journal of Pharmacology
1995
Corpus ID: 4531962
1993
1993
Effects of isoquinoline derivatives, HA1077 and H-7, on cytosolic Ca2+ level and contraction in vascular smooth muscle.
S. Takizawa
,
M. Hori
,
H. Ozaki
,
H. Karaki
European Journal of Pharmacology
1993
Corpus ID: 4542915
Highly Cited
1987
Highly Cited
1987
Mechanism of action of a novel antivasospasm drug, HA1077.
T. Asano
,
I. Ikegaki
,
+4 authors
H. Hidaka
Journal of Pharmacology and Experimental…
1987
Corpus ID: 13625985
HA1077, but not the potent calcium entry blocker nicardipine reversed experimental chronic cerebral vasospasm induced in a two…
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