exonuclease activity

Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end. [GOC:mah, ISBN:0198547684]
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Lassa fever virus, a member of the family Arenaviridae, is a highly endemic category A pathogen that causes 300,000-500,000… (More)
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Highly Cited
2009
Highly Cited
2009
Nuclear and cytoplasmic forms of the yeast exosome share 10 components, of which only Rrp44/Dis3 is believed to possess 3… (More)
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Highly Cited
2001
Highly Cited
2001
Saccharomyces cerevisiae RAD50 and MRE11 genes are required for the nucleolytic processing of DNA double-strand breaks. We have… (More)
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2001
2001
Werner syndrome (WS) is characterized by the early onset of symptoms of premature aging, cancer, and genomic instability. The… (More)
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Highly Cited
1998
Highly Cited
1998
MRE11 and RAD50 are known to be required for nonhomologous joining of DNA ends in vivo. We have investigated the enzymatic… (More)
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Highly Cited
1998
Highly Cited
1998
The human DNA polymerase gamma catalytic subunit was overexpressed in recombinant baculovirus-infected insect cells, and the 136… (More)
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Highly Cited
1996
Highly Cited
1996
Highly purified p53 protein from different sources was able to degrade DNA with a 3'-to-5' polarity, yielding deoxynucleoside… (More)
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Highly Cited
1991
Highly Cited
1991
The 5'----3' exonuclease activity of the thermostable enzyme Thermus aquaticus DNA polymerase may be employed in a polymerase… (More)
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Highly Cited
1989
Highly Cited
1989
The 3' to 5' exonuclease activity of bacteriophage T7 DNA polymerase (gene 5 protein) can be inactivated selectively by reactive… (More)
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Highly Cited
1987
Highly Cited
1987
A chemically modified phage T7 DNA polymerase has three properties that make it ideal for DNA sequencing by the chain-termination… (More)
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