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estrogen biosynthetic process

Known as: estrogen synthesis, estrogen biosynthesis, oestrogen biosynthesis 
The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual… (More)

Topic mentions per year

Topic mentions per year

1950-2017
020406019502016

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2 relations
negative regulation of estrogen biosynthetic processregulation of estrogen biosynthetic process

Related mentions per year

Related mentions per year

1951-2018
1960198020002020
estrogen biosynthetic process
regulation of estrogen biosynthetic process
negative regulation of estrogen biosynthetic process

Papers overview

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Highly Cited
2007
Highly Cited
2007
GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis.
The recent development of hormonal therapy that blocks estrogen synthesis represents a major advance in the treatment of estrogen… (More)
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Highly Cited
2004
Highly Cited
2004
Association of frequency and duration of aspirin use and hormone receptor status with breast cancer risk.
CONTEXT Use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) has been associated with a decrease in the risk of… (More)
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Highly Cited
2004
Highly Cited
2004
Hippocampal synapses depend on hippocampal estrogen synthesis.
Estrogens have been described to induce synaptogenesis in principal neurons of the hippocampus and have been shown to be… (More)
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Highly Cited
2000
Highly Cited
2000
Vitamin D is an important factor in estrogen biosynthesis of both female and male gonads.
In the present study, the role of vitamin D in the regulation of estrogen synthesis in gonads was investigated. Vitamin D… (More)
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Highly Cited
1999
Highly Cited
1999
Androgen and follicle-stimulating hormone interactions in primate ovarian follicle development.
We have previously shown that androgens stimulate early stages of follicular development and that granulosal androgen receptor… (More)
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Highly Cited
1999
Highly Cited
1999
Correlation of aromatase and cyclooxygenase gene expression in human breast cancer specimens.
Aromatase, the enzyme system catalyzing estrogen biosynthesis, is found in stromal tissue in the breast. The increased expression… (More)
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Highly Cited
1999
Highly Cited
1999
Aromatase expression by astrocytes after brain injury: implications for local estrogen formation in brain repair.
Recent evidence indicates that 17beta-estradiol may have neuroprotective and neuroregenerative properties. Estradiol is formed… (More)
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Highly Cited
1996
Highly Cited
1996
Estrogen biosynthesis proximal to a breast tumor is stimulated by PGE2 via cyclic AMP, leading to activation of promoter II of the CYP19 (aromatase) gene.
In the present report, we show that prostaglandin (PG) E2 is the most potent factor which stimulates aromatase expression via… (More)
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Highly Cited
1993
Highly Cited
1993
A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction…
C19 steroids are converted to estrogens in a number of tissues by a specific form of cytochrome P450, namely aromatase cytochrome… (More)
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Highly Cited
1989
Highly Cited
1989
Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis.
The structural gene encoding aromatase cytochrome P-450 (P-450AROM) was isolated from human genomic DNA. The gene spans at least… (More)
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