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Prenatal Phenol and Phthalate Exposures and Birth Outcomes

TLDR
The association of 2,5-DCP and BP3 with reduced or increased birth weight could be important in very early or small-size births, and positive associations of urinary metabolites with some outcomes may be attributable partly to unresolved confounding with maternal anthropometric factors.
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Risk of breast cancer and organochlorine exposure.

TLDR
There is no evidence for an association of breast cancer risk with DDE or PCB levels in blood (based on samples collected during the period 1987-1992) nor with their elimination half-lives, however, changes in DDE and PCBs over time are influenced by metabolism, BMI, and current OC exposures, and each may affect interpretation of OC levels in risk assessment models.
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Blood levels of organochlorine residues and risk of breast cancer.

TLDR
In this population of New York City women, breast cancer was strongly associated with DDE in serum but not with PCBs, suggesting that environmental chemical contamination with organochlorine residues may be an important etiologic factor in breast cancer.
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Prenatal Exposure to Organophosphates, Paraoxonase 1, and Cognitive Development in Childhood

TLDR
It is suggested that prenatal exposure to organophosphates is negatively associated with cognitive development, particularly perceptual reasoning, with evidence of effects beginning at 12 months and continuing through early childhood.
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Pilot Study of Urinary Biomarkers of Phytoestrogens, Phthalates, and Phenols in Girls

TLDR
A wide spectrum of hormonally active exposure biomarkers were detectable and variable among young girls, with high maximal concentrations > 1,000 μg/L found for several analytes and varied by characteristics that may be relevant to development.
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Temporal variability in urinary concentrations of phthalate metabolites, phytoestrogens and phenols among minority children in the United States.

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In utero pesticide exposure, maternal paraoxonase activity, and head circumference.

TLDR
The effects of pesticide exposure on birth weight, length, head circumference, and gestational age among 404 births between May 1998 and May 2002 are evaluated and chlorpyrifos may have a detrimental effect on fetal neurodevelopment among mothers who exhibit low PON1 activity.
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Breast cancer and serum organochlorines: a prospective study among white, black, and Asian women.

TLDR
The data do not support the hypothesis that exposure to DDE and PCBs increases risk of breast cancer, and the lack of association between exposure to organochlorines and breast cancer was present regardless of length of follow-up, year of diagnosis, or the case patient's menopausal and estrogen-receptor status.
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Prenatal organophosphate metabolite and organochlorine levels and performance on the Brazelton Neonatal Behavioral Assessment Scale in a multiethnic pregnancy cohort.

TLDR
The authors uncovered additional evidence that prenatal levels of organophosphate pesticide metabolites are associated with anomalies in primitive reflexes, which are a critical marker of neurologic integrity.
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DDT and Breast Cancer in Young Women: New Data on the Significance of Age at Exposure

TLDR
Exposure to p,p′-DDT early in life may increase breast cancer risk, and many U.S. women heavily exposed to DDT in childhood have not yet reached 50 years of age; the public health significance of DDT exposure in early life may be large.
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