negative regulation of estrogen biosynthetic process

Known as: down-regulation of estrogen biosynthesis, down-regulation of estrogen biosynthetic process, down regulation of oestrogen biosynthesis 
Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process. [GO_REF:0000058, GOC:TermGenie, PMID… (More)
National Institutes of Health

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Broader (1)

biological control
estrogen biosynthetic process

Papers overview

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2013
2013
Estrogen receptor-α36 is involved in development of acquired tamoxifen resistance via regulating the growth status switch in breast cancer cells.
Acquired tamoxifen (TAM) resistance limits the therapeutic benefit of TAM in patients with hormone-dependent breast cancer. The… (More)
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2007
2007
Estrogen receptor-alpha mediates an intraovarian negative feedback loop on thecal cell steroidogenesis via modulation of Cyp17a1 (cytochrome P450, steroid 17alpha-hydroxylase/17,20 lyase) expression.
Excess androgen synthesis by thecal cells is invariably detrimental to preovulatory follicles in the ovary and is considered a… (More)
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Highly Cited
2005
Highly Cited
2005
Evidence that oestrogen receptor-α plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver
We used oestrogen receptor-α (ERα) knockout (ERKO) and receptor-β (ERβ) knockout (BERKO) mice to investigate the mechanism(s… (More)
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Review
2004
Review
2004
The insulin-like growth factor system in advanced breast cancer.
Despite improvements in therapy, the prognosis for advanced breast cancer is poor and a search for new treatment targets and key… (More)
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2004
2004
Embryonic exposure to oestrogen causes eggshell thinning and altered shell gland carbonic anhydrase expression in the domestic hen.
Eggshell thinning among wild birds has been an environmental concern for almost half a century. Although the mechanisms for… (More)
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2003
2003
The effects of 2-substituted oestrogen sulphamates on the growth of prostate and ovarian cancer cells
The human endogenous metabolite 2-methoxyoestradiol (2-MeOE2) has been shown to inhibit the proliferation of breast cancer cells… (More)
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Review
2003
Review
2003
Homology modelling of the nuclear receptors: human oestrogen receptorbeta (hERbeta), the human pregnane-X-receptor (PXR), the Ah receptor (AhR) and the constitutive androstane receptor (CAR) ligand…
We have generated by homology the three-dimensional structures of the ligand binding domain (LBD) of several interrelated human… (More)
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2002
2002
Effects of waterborne exposure of octylphenol and oestrogen on pregnant viviparous eelpout (Zoarces viviparus) and her embryos in ovario.
Exposure to oestrogenic chemicals (xeno-oestrogens) may have severe effects on embryonic development. The present study… (More)
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1998
1998
Inhibition of barnacle settlement by the environmental oestrogen 4-nonylphenol and the natural oestrogen 17β oestradiol
 
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Highly Cited
1990
Highly Cited
1990
Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen.
Various oestrogen responsive reporter genes and vectors expressing truncated or chimeric human oestrogen receptors (hER… (More)
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