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negative regulation of estrogen biosynthetic process

Known as: down-regulation of estrogen biosynthesis, down-regulation of estrogen biosynthetic process, down regulation of oestrogen biosynthesis 
Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process. [GO_REF:0000058, GOC:TermGenie, PMID… Expand
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

biological control
estrogen biosynthetic process

Papers overview

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Highly Cited
2013
Highly Cited
2013
Estrogen receptor‐α36 is involved in development of acquired tamoxifen resistance via regulating the growth status switch in breast cancer cells
Acquired tamoxifen (TAM) resistance limits the therapeutic benefit of TAM in patients with hormone‐dependent breast cancer. The… Expand
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Highly Cited
2007
Highly Cited
2007
Estrogen receptor‐α mediates an intraovarian negative feedback loop on thecal cell steroidogenesis via modulation of Cyp17a1 (cytochrome P450, steroid 17α‐hydroxylase/17,20 μlyase) expression
Excess androgen synthesis by thecal cells is invariably detrimental to preovulatory follicles in the ovary and is considered a… Expand
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Highly Cited
2005
Highly Cited
2005
Evidence that oestrogen receptor-α plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver
Aims/hypothesisWe used oestrogen receptor-α (ERα) knockout (ERKO) and receptor-β (ERβ) knockout (BERKO) mice to investigate the… Expand
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Highly Cited
2004
Highly Cited
2004
Embryonic exposure to oestrogen causes eggshell thinning and altered shell gland carbonic anhydrase expression in the domestic hen.
Eggshell thinning among wild birds has been an environmental concern for almost half a century. Although the mechanisms for… Expand
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2003
2003
The effects of 2-substituted oestrogen sulphamates on the growth of prostate and ovarian cancer cells
The human endogenous metabolite 2-methoxyoestradiol (2-MeOE2) has been shown to inhibit the proliferation of breast cancer cells… Expand
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2002
2002
Effects of waterborne exposure of octylphenol and oestrogen on pregnant viviparous eelpout (Zoarces viviparus) and her embryos in ovario.
Exposure to oestrogenic chemicals (xeno-oestrogens) may have severe effects on embryonic development. The present study… Expand
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2001
2001
Metabolism of bisphenol A in isolated rat hepatocytes and oestrogenic activity of a hydroxylated metabolite in MCF-7 human breast cancer cells
1. The metabolites of bisphenol A (BPA; 2,2-bis(4-hydroxyphenyl)propane) in freshly isolated rat hepatocytes and the oestrogenic… Expand
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1992
1992
Oestrogen receptor gene structure and function in breast cancer
The mechanisms underlying loss of oestrogen responsiveness in breast cancer are not well-defined. Potential mechanisms include… Expand
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1992
1992
Oestrogen sulphatase activity in hormone‐dependent and hormone‐independent breast‐cancer cells: Modulation by steroidal and non‐steroidal therapeutic agents
Oestrogen sulphatase may play an important role in providing intracellular oestrogens from E1S for the growth and maintenance of… Expand
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Highly Cited
1990
Highly Cited
1990
Role of the two activating domains of the oestrogen receptor in the cell‐type and promoter‐context dependent agonistic activity of the anti‐oestrogen 4‐hydroxytamoxifen.
Various oestrogen responsive reporter genes and vectors expressing truncated or chimeric human oestrogen receptors (hER… Expand
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