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eponemycin

Known as: 1,2-epoxy-2-hydroxymethyl-4-(N-isooctanoylserylamino)-6-methylhept-6-ene-3-one, Heptanamide, N-(1-(hydroxymethyl)-2-((1-((2-(hydroxymethyl)oxiranyl)carbonyl)-3-methyl-3-butenyl)amino)-2-oxoethyl)-6-methyl- 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

AmidesSerine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Analysis of eponemycin (a'?' epoxyketone) analog compound from Streptomyces hygroscopicus subsp Hygroscopicus extracts and its antiplasmodial activity during Plasmodium berghei infection
Background & objectives: The greatest challenge in reducing the high mortality and morbidity of malaria is due to the emerging… 
2017
2017
Mechanism of pharmacophore biosynthesis for epoxyketone proteasome inhibitors
Natural α,β-epoxyketone proteasome inhibitors produced primarily by Streptomyces species, such as TMC-86A, are potent anticancer… 
2013
2013
Metabolite extract of Streptomyces hygroscopicus Hygroscopicus inhibit the growth of Plasmodium berghei through inhibition of ubiquitin - proteasome system.
Streptomyces hygroscopicus Hygroscopicus, a member of family of Actinomycetes produces eponemycin a proteasome inhibitor that can… 
Review
2005
Review
2005
Proteasome inhibitors in cancer therapy: death by indigestion
As Eugene Garfield said, while it is easy to recognize a good paper, it could be more difficult to recognize a bad paper. In fact… 
2003
2003
Eponemycin and Epoxomicin analogues and their uses
The present invention provides compounds having the formula (I) The present invention provides novel (Epoxomicin) and eponemycin… 
1997
1997
Inhibition of Angiogenesis by Rhizoxin, a Microbial Metabolite Containing Two Epoxide Groups
Previous studies by our and other groups have shown that microbial products containing more than one epoxide group, including… 
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