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emedastine

Known as: Emedastinum, 1-(2-Ethoxy-ethyl)-2-(4-methyl-[1,4]diazepan-1-yl)-1H-benzoimidazole, 1-(2-Ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazole 
A second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (3)

Anti-Allergic AgentsBenzimidazolesHistamine H1 Antagonists
Conjunctivitis, Acute HemorrhagicDrug AllergyHistamine H1 Receptor Antagonists [MoA]emedastine difumarate

Narrower (2)

EmadineKB 2413

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Site-isolated manganese carbonyl on bipyridine-functionalities of periodic mesoporous organosilicas: efficient CO2 photoreduction and detection of key reaction intermediates† †Electronic…
Robust heterogeneous bipyridine-based periodic mesoporous organosilica manganese catalysts are highly active for CO2… 
2008
2008
Green phosphorescent iridium dendrimers containing dendronized benzoimidazole-based ligands for OLEDs
2008
2008
Comparative efficacy of topical antihistamines in an animal model of early phase allergic conjunctivitis.
2005
2005
Biopharmaceutical considerations on antihistamine effects of topically administered emedastine.
Antihistamine effects of emedastine applied topically with three vehicles varying in their polarities were investigated in rats… 
Highly Cited
2002
Highly Cited
2002
Effects of emedastine and cetirizine, alone and with alcohol, on actual driving of males and females
Emedastine is registered in its country of origin (Japan) as an antihistamine for the indication of seasonal allergic rhinitis… 
2000
2000
Safety and Efficacy Comparison of Emedastine 0.05% Ophthalmic Solution Compared to Levocabastine 0.05% Ophthalmic Suspension in Pediatric Subjects with Allergic Conjunctivitis
. Purpose: To determine the efficacy and tolerance of emedastine 0.05% ophthalmic solution compared to levocabastine 0.05… 
2000
2000
Safety and efficacy comparison of emedastine 0.05% ophthalmic solution compared to levocabastine 0.05% ophthalmic suspension in pediatric subjects with allergic conjunctivitis. Emadine Study Group.
PURPOSE To determine the efficacy and tolerance of emedastine 0.05% ophthalmic solution compared to levocabastine 0.05… 
Highly Cited
1998
Highly Cited
1998
Histamine-Stimulated Cytokine Secretion from Human Conjunctival Epithelial Cells: Inhibition by the Histamine H1 Antagonist Emedastine
The present studies demonstrate that histamine induces the secretion of IL-6, IL-8 and GM-CSF from human conjunctival epithelial… 
1998
1998
Characterization of antihistamines using biphasic cutaneous reaction in BALB/c mice.
1996
1996
Hepatic echinococcus disease: our experience over 22 years.
BACKGROUND/AIMS It is important to single out the indications for surgery of hydatid disease of the liver at an early stage. For… 
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