Skip to search formSkip to main contentSkip to account menu

emedastine difumarate

Known as: 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate 
The difumarate salt form of emedastine, a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine… 
National Institutes of Health

Related topics

Related topics

4 relations
Conjunctivitis, Acute HemorrhagicDrug AllergyHistamine H1 Receptor Antagonists [MoA]emedastine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Effect of Emedastine Difumarate on CC Chemokine-Elicited Eosinophil Migration
Emedastine difumarate (emedastine) is an antiallergic drug found among the derivatives which has a series of benzimidazole frames… 
2000
2000
Emedastine ophthalmic solution 0.05% versus levocabastine ophthalmic suspension 0.05% in the treatment of allergic conjunctivitis using the conjunctival allergen challenge model.
1994
1994
Preclinical efficacy of emedastine, a potent, selective histamine H1 antagonist for topical ocular use.
Emedastine [1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)- benzimidazole difumarate] was evaluated for topical ocular anti… 
1993
1993
Inhibitory effects of emedastine difumarate on histamine release.
The inhibitory effects of emedastine difumarate on histamine release were studied in rat peritoneal mast cells. Emedastine… 
1993
1993
Effects of Emedastine Difumarate on the Chemotaxis of Guinea Pig Eosinophils and Human Eosinophils.
Emedastine difumarateは抗histamine作用およびhistamine遊離抑制作用を有する抗アレルギー薬である。本研究では, アレルギー性炎症の増悪に深く関与していると考えられている好酸球の遊走に対するemedastine… 
1987
1987
The Biological Fate of 1-(2-Ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate (KB-2413) III
The absorption and excretion of 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate (KB-2413) were studied… 
1986
1986
Comparative study of various H1-blockers on neuropharmacological and behavioral effects including 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate (KB-2413), a new…
In a conditioned avoidance response tested in rats, all of the H1-blockers employed caused a dose-related inhibition at doses 5… 
1986
1986
Determination of the antiallergic agent KB-2413 in plasma by means of capillary gas chromatography with a nitrogen-sensitive detector.
A gas chromatographic method for the quantitative determination of the new antiallergic agent, 1-(2-ethoxyethyl)-2-(4-methyl-1… 
1984
1984
Effect of 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimida zole difumarate (KB-2413), a new antiallergic, on chemical mediators.
Effects of 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazol e difumarate (KB-2413) on chemical mediators were… 
1984
1984
Antiallergic effect of 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidaz ole difumarate (KB-2413).
Antiallergic effects of 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazol e difumarate (KB-2413) were investigated in… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)